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D-Glucuronolactone Side Effects

Glucuronolactone is a natural, white solid compound. It is odorless and soluble in hot and cold water. Glucuronolactone is commonly used as a detoxifier in energy drinks. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is D-Glucuronolactone?

D-Glucuronolactone is used as a supplement in certain sports energy drinks; most notably Red Bull. Glucuronolactone is implicated as an agent which may be helpful for enhancing cardiovascular functioning, improving athletic performance and promoting alertness.

Possible Side Effects of D-Glucuronolactone

Glucuronolactone is widely consumed in energy drinks and is generally well tolerated. There are no safety warnings issued by the FDA for this supplement. Also, the EFSA (European Food Safety Association) has stated that there is no risk of glucuronolactone toxicity due to exposure from routine consumption of certain energy drinks.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. D-Glucuronolactone is considered safe.

Suggested Dosage

Doses of 350mg glucuronolactone have been found to be effective for use as a pre workout supplement (Hoffman et al, 2008). The effects of glucuronolactone set in fairly rapidly. It has been reported that consuming a supplement containing glucuronolactone 10 minutes before exercise resulted in improved exercise performance (Hoffman et al, 2008). However, given that glucuronolactone typically occurs with other ingredients, it is recommended for such supplements to be consumed 30 to 45 minutes before a workout, or as indicated by the manufacturer.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to D-Glucuronolactone populations. Better consult to your doctor if you would like to intake D-Glucuronolactone.

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Polysorbate 20 Side Effects

Polysorbate 20 E432 is a polysorbate-type nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid. Though Polysorbate 20 E432 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Polysorbate 20 E432?

Polysorbate 20 E432 is a yellow to amber liquid with a faint odor and a warm, somewhat bitter taste. This product is a mixture of laurate, partial esters of sorbitol, and sorbitol anhydrides condensed with 20moles of ethylene oxide. It is commonly used as a wetting agent in flavored mouth drops to spread the feeling of other ingredients such as mint flavor, but it can also be used in food as a flavoring ingredient.

Possible Side Effects of Polysorbate 20 E432

Polysorbate 20 E432 is generally recognised safe. The possible side-effects that may: Eye irritation

GRAS Affirmation: No

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Polysorbate 20 E432 is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Genistein populations. Better consult to your doctor if you would like to intake Polysorbate 20.

Related Research

1. The effects of membrane filters used in biopharmaceutical processes on the concentration and composition of polysorbate 20. [Biotechnol Prog. 2013 Nov-Dec] Author: Lei M, Hewitt D, Cornell C, Skidmore K, Kao YH, Sugahara J, Beane D, Ji J.

2. Characterization and stability study of polysorbate 20 in therapeutic monoclonal antibody formulation by multidimensional ultrahigh-performance liquid chromatography-charged aerosol detection-mass spectrometry. [Anal Chem. 2014 May 20] Author: Li Y, Hewitt D, Lentz YK, Ji JA, Zhang TY, Zhang K.

3. The effects of membrane filters used in biopharmaceutical processes on the concentration and composition of polysorbate 20. [Biotechnol Prog. 2013 Nov-Dec] Author: Lei M, Hewitt D, Cornell C, Skidmore K, Kao YH, Sugahara J, Beane D, Ji J.

4. Alcohols Effect on Critic Micelle Concentration of Polysorbate 20 and Cetyl Trimethyl Ammonium Bromine Mixed Solutions. [J Surfactants Deterg. 2013 Jul] Author: Sidim T, Acar G.

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Polysorbate 80 Side Effects

Polysorbate 80 E433 also known as Tween 80.It is an amber/golden-colored viscous liquid. It is made from polyethoxylated sorbitan (chemical compounds derived from the dehydration of sugar alcohol) and oleic acid, a fatty acid found in animal and vegetable fats. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Polysorbate 80 E433?

Polysorbate 80 E433 is a colorless to yellow liquid used as an emulsifier in foods. It is used in ice cream to make it smoother, easier to handle, and to increase its resistance to melting.

Possible Side Effects of Polysorbate 80 E433

Polysorbate 80 E433 is generally recognised as safe, the side effect may Cough; mild pain at the injection site; mild stomach pain..

GRAS Affirmation: No

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Polysorbate 80 E433 is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Polysorbate 80 populations. Better consult to your doctor if you would like to intake Polysorbate 80 E433.

 

Related Research

1. [Advance of polysorbate 80 for injection accessories]. [Zhongguo Zhong Yao Za Zhi. 2011 Jul] Author: Zhang M.

2. Development of Polysorbate 80/Phospholipid mixed micellar formation for docetaxel and assessment of its in vivo distribution in animal models. [Nanoscale Res Lett. 2011 Apr 20] Author: Song H, Geng H, Ruan J, Wang K, Bao C, Wang J, Peng X, Zhang X, Cui D.

3. Polysorbate 80 inhibition of Pseudomonas aeruginosa biofilm formation and its cleavage by the secreted lipase LipA. [Antimicrob Agents Chemother. 2009 Jan] Author: Toutain-Kidd CM, Kadivar SC, Bramante CT, Bobin SA, Zegans ME.

4. Permeabilisation and solubilisation of soybean phosphatidylcholine bilayer vesicles, as membrane models, by polysorbate, Tween 80. [Eur J Pharm Sci. 2005 Nov] Author: Simões SI, Tapadas JM, Marques CM, Cruz ME, Martins MB, Cevc G.

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Sodium stearoyl lactylate Side Effects

Sodium stearoyl lactylate, or SSL, is used as a food emulsifier in baked goods and processed foods, including breads, sour cream, salad dressings, soups, cheese products, crackers, cookies and puddings. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Sodium stearoyl lactylate?

Sodium Stearoyl Lactylate (Powder) is a non-toxic, biodegradable FDA approved food additive. It can strengthen dough, mixes liquids and oils together, and it can even replace some fat and sugar.

Possible Side Effects of Sodium stearoyl lactylate

Sodium stearoyl lactylate is generally used as safe ingredient, the side effects may may cause slight skin or eye irritation, and if inhaled in its pure form, it may be slightly irritating to the respiratory tract.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium stearoyl lactylate is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sodium stearoyl lactylate populations. Better consult to your doctor if you would like to intake Sodium stearoyl lactylate.

Related Research

1. Impact of mixing time and sodium stearoyl lactylate on gluten polymerization during baking of wheat flour dough. [Food Chem. 2013 Dec 15] Author: Van Steertegem B, Pareyt B, Brijs K, Delcour JA.

2. [LC-MS analysis of commercial sodium stearoyl lactylate components]. [Shokuhin Eiseigaku Zasshi. 2012] Author: Kubota H, Mikawa T, Ozeki Y, Sato K, Akiyama H.

3. Use of sodium stearoyl lactylate and azodicarbonamide in wheat flour breads with added pea flour. [Int J Food Sci Nutr. 2011 Jun] Author: Alasino MC, Osella CA, De La Torre MA, Sanchez HD.

4. Allergic contact dermatitis from sodium stearoyl lactylate, an emulsifier commonly used in food products. [Contact Dermatitis. 2005 Aug] Author: Jensen CD, Andersen KE.

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Sodium Stearate Side Effects

Sodium stearate is the sodium salt of stearic acid. This white solid is the most common soap. It is found in many types of solid deodorants, rubbers, latex paints, and inks. It is also a component of some food additives and food flavorings. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Sodium Stearate?

Sodium stearate is primarily used to make soap. It is mostly used to create soap bases, but it is also used to produce deodorants, latex paints, rubbers and inks, and to a lesser extent, food additives and flavorings.

Possible Side Effects of Sodium Stearate

Sodium stearate has a long history of safe use in personal care products. It is permitted for direct addition to food by the U.S. Food and Drug Administration. The side effects may: Irritability, Allergy, Itching, Stinging,Skin Irritation

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium Stearate is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sodium Stearate populations. Better consult to your doctor if you would like to intake Sodium Stearate.

 

 

Related Research

1. Dissolution of a poorly water-soluble drug dry coated with magnesium and sodium stearate. [Eur J Pharm Biopharm. 2012 Feb] Author: Tay T, Morton DA, Gengenbach TR, Stewart PJ.

2. Cation-controlled crystal growth of silver stearate: cryo-TEM investigation of lithium vs sodium stearate. [Langmuir. 2010 Feb 16] Author: Dong J, McCormick AV, Davis HT, Whitcomb DR.

3. Precipitation of different calcite crystal morphologies in the presence of sodium stearate. [J Colloid Interface Sci. 2009 Jan 1] Author: Ukrainczyk M, Kontrec J, Kralj D.

4. Comparative studies on additive effects of sodium dodecylbenzensulfonate and sodium stearate on uptake of chemicals by willow shiner (Gnathopogon caerulescens). [Comp Biochem Physiol C. 1987] Author: Nakanishi H, Tsuda T, Fukui S, Hirayama T.

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Potassium Stearate Side Effects

Potassium stearate, one of many stearate salts, is used in the formulation of cosmetics and personal care products. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Potassium Stearate?

Potassium Stearate is an emulsifier: it prevents the oily and liquid parts of a formula from separating.
It can also increase the thickness of the oil portions of cosmetic products.

Possible Side Effects of Potassium Stearate

Potassium Stearate is generally considered to be safe.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Potassium Stearate is considered safe by FDA according to existing data and granted GRAS status.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Potassium Stearate populations. Better consult to your doctor if you would like to intake Potassium Stearate.

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Polyglycerol Esters of Fatty Acids Side Effects

Polyglycerol esters of fatty acids E475 is is made up of polyglycerol and fatty acid esterification. It has a wide HLB value, good emulsifying ability and less dosage. It is a kind of new type, high efficiency and good performance of food emulsifier. Though Polyglycerol esters of fatty acids E475 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Polyglycerol Esters of Fatty Acids E475?

Polyglycerol Esters of Fatty Acid E475 is nonionic emulsifiers that are allowed for food use in many countries. In addition to the stabilization of emulsions, foams, and dispersions, polyglycerol esters can act as aerating agents, dough strengtheners, rheology modifiers, crystal modifiers, antispattering agents, beverage clouding agents, humectants, solubilizers, or fat substitutes

Possible Side Effects of Polyglycerol Esters of Fatty Acids E475

Polyglycerol Esters of Fatty Acids E475 is generally considered a safe ingredient. None known. The body metabolises all components identical to natural fat.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Polyglycerol Esters of Fatty Acids E475 is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Polyglycerol Esters of Fatty Acids populations. Better consult to your doctor if you would like to intake Polyglycerol Esters of Fatty Acids.

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Non dairy creamer Side Effects

Non-dairy creamers or coffee whiteners are liquid or granular substances intended to substitute for milk or cream as an additive to coffee, tea, hot chocolate or other beverages. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Non dairy creamer ?

Non dairy creamer is a white flakes or a white granular product or may be a solid with strong hygroscopicity, it may be soluble in water, alcohol and glycerine, insoluble in acetone or diethyl ether. Sodium Hydroxide may be used in acid neutralizing, discoloring, and deodorizing.

Possible Side Effects of Non dairy creamer

Non-dairy creamers is generally considered a safe ingredient. The side effects may:

  • nausea
  • dizziness
  • vomiting
  • inflammation
  • blood sugar spike

GRAS Affirmation: No

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Though Non dairy creamer is not on FDA’s GRAS exemption list, it’s still widely accepted as safe food additive in many countries including USA with specific limit on dosage.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Non dairy creamer populations. Better consult to your doctor if you would like to intake Non dairy creamer .

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Glycerol monostearate Side Effects

Glycerol monostearate, commonly known as GMS, is an organic molecule used as an emulsifier. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Glycerol monostearate?

Glycerol monostearate also known as Distilled Monoglyceride (DMG), is a high efficient food emulsifier with many uses including; emulsifying, dispersing, stabilizing, foaming, defoaming and starch anti-aging. It is widely used in food, medicine, daily chemicals, plastics, packaging and cosmetics industries, DMG is completely non-toxic and harmless to humans, but body intake is not unlimited.

Possible Side Effects of Glycerol monostearate

Glycerol monostearate is generally considered a safe ingredient. The side effects may cause nausea, diarrhea, dehydration.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Glycerol monostearate is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Glycerol monostearate populations. Better consult to your doctor if you would like to intake Glycerol monostearate.

Related Research

1. Design of lipid matrix particles for fenofibrate: effect of polymorphism of glycerol monostearate on drug incorporation and release. [J Pharm Sci. 2014 Feb] Author: Xia D, Cui F, Gan Y, Mu H, Yang M.

2. A study of a co-processed dry binder composed of microcrystalline cellulose and glycerol monostearate. [Ceska Slov Farm. 2012 Oct] Author: Mužíková J, Muchová S.

3. Enhancing reaction rate of transesterification of glycerol monostearate and methanol by CO(2). [J Phys Chem A. 2007 Nov 29] Author: Song J, Hou M, Jiang T, Han B, Li X, Liu G, Yang G.

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Triacetin Side Effects

The triglyceride 1,2,3-triacetoxypropane is more generally known as triacetin E1518 and glycerin triacetate. It is the triesterof glycerol and acetylating agents, such as acetic acid and acetic anhydride. Though Triacetin E1518 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Triacetin E1518?

Triacetin is a colorless liquid. This product acts as a solvent in flavorings. Triacetin E1518 is used in applications such as baked goods, beverages, chewing gum, flavoring agents, dairy desserts and humectant.

Possible Side Effects of Triacetin E1518

Triacetin E1518 is generally considered a safe ingredient. The possible side effects like Irritation.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Triacetin E1518 is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Triacetin populations. Better consult to your doctor if you would like to intake Triacetin.

Related Research

1. Structural changes and triacetin migration of starch acetate film contacting with distilled water as food simulant. [Carbohydr Polym. 2014 Apr 15] Author: Zhu J, Li X, Huang C, Chen L, Li L.

2. Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma. [Int J Cancer. 2014 Mar 15] Author: Tsen AR, Long PM, Driscoll HE, Davies MT, Teasdale BA, Penar PL, Pendlebury WW, Spees JL, Lawler SE, Viapiano MS, Jaworski DM.

3. Final report on the safety assessment of triacetin. [Int J Toxicol. 2003] Author: Fiume MZ; Cosmetic Ingredients Review Expert Panel.

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DATEM Side Effects

DATEM (diacetyl tartaric acid ester of mono- and diglycerides, also E472e) is an emulsifier primarily used in baking to create a strong gluten network in dough. It is added to crusty breads, such as rye to impart a springy, chewy texture, as well as in the production of biscuits, coffee whiteners, salsa con queso, ice cream, and salad dressings. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is DATEM?

DATEM is an ivory white powder or particle solid. This product has the functions to emulsify, increase stabilization, improve preservation, prolong shelf life, and protect freshness, etc. It is mainly used as an additive in bread, cake, butter, hydrogenated vegetable oil and vegetable oil powder. It can also be used as an emulsifier, dispersion agent to improve emulsification and the intermiscibility between oil and water.

Possible Side Effects of DATEM

DATEM is generally considered a safe ingredient. DATEM side effects may: heart fibrosis and adrenal overgrowth (found in animal studies)

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. DATEM is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to DATEM populations. Better consult to your doctor if you would like to intake DATEM.

Related Research

1. The compound DATEM inhibits respiratory syncytial virus fusion activity with epithelial cells. [Antiviral Res. 2003 Apr] Author: Ohki S, Liu JZ, Schaller J, Welliver RC. 2. Study of the effect of DATEM. 1. Influence of fatty acid chain length on rheology and baking. [J Agric Food Chem. 1999 May] Author: Köhler P, Grosch W.

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Calcium Stearoyl Lactylate

Calcium Stearoyl Lactylate Side Effects

Calcium Stearoyl Lactylate appears as an ivory white powder or lamellar solid. It can be used as an emulsifier and as a preservative. Though Calcium Stearoyl Lactylate’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Calcium Stearoyl Lactylate?

Calcium Stearoyl Lactylate functions to increase toughness, emulsify, improve preservation, keep fresh, etc. It is often used in baked goods, steamed breads, noodles and dumplings.

Possible Side Effects of Calcium Stearoyl Lactylate

Calcium Stearoyl Lactylate is generally considered a safe ingredient. It may irritate eye, skin and lung if eye, skin contact or inhalation occurs.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Calcium Stearoyl Lactylate is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Calcium Stearoyl Lactylate populations. Better consult to your doctor if you would like to intake Calcium Stearoyl Lactylate.

 

 

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Stearic Acid Side Effects

Stearic acid, a saturated fatty acid, is also known as octadecanoic acid. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Stearic acid?

Stearic Acid is used in a multitude of products that we use every day like shaving cream, cosmetics, medicines, skincare products, soaps, detergents and candles. It is also used in the manufacturing process of many more products because this renewable fatty acid is extremely versatile. Stearic Acid is also used as a mold release for hard/pressed candies.

Possible Side Effects of Stearic acid

Stearic acid is generally considered a safe ingredient, the side effects may:

  • Skin Irritations: Irritations of the skin may be accompanied by severe itching and often time redness and swelling.There are also rash-like symptoms that may occur like small red spots.
  • Sensitivity of the Skin: One of the milder side effects of stearic acid is making the skin sensitive to substances and direct exposure to the sun.
  • Damage of the Skin: In certain occasions, hive-like spots may occur in the skin which will often turn into blisters that can damage the skin. There are also times wherein the skin will turn scaly.

GRAS Affirmation: No

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Stearic acid is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Stearic acid populations. Better consult to your doctor if you would like to intake Stearic acid.

Related Research

1. Optimizing the preparation procedure of self-assembled monolayer of stearic acid for protection of cupronickel alloy. [Acta Chim Slov. 2014] Author: Marušić K, Hajdari Z, Ćurković HO.

2. Invited review: Palmitic and stearic acid metabolism in lactating dairy cows. [J Dairy Sci. 2014 Aug] Author: Loften JR, Linn JG, Drackley JK, Jenkins TC, Soderholm CG, Kertz AF.

3. Deletions of the SACPD-C locus elevate seed stearic acid levels but also result in fatty acid and morphological alterations in nitrogen fixing nodules. [BMC Plant Biol. 2014 May 27] Author: Gillman JD, Stacey MG, Cui Y, Berg HR, Stacey G.

4. Impact of stearic acid and oleic acid on hemostatic factors in the context of controlled diets consumed by healthy men. [Eur J Clin Nutr. 2014 Sep] Author: Gebauer SK, Tracy RP, Baer DJ.

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Sodium Hydroxide Side Effects

Sodium hydroxide E524, also known as lye and caustic soda, is an inorganic compound with formula NaOH. Though Sodium hydroxide E524 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Sodium Hydroxide E524?

Sodium Hydroxide (Caustic Soda) is a white flakes or a white granular product or may be a solid with strong hygroscopicity, it may be soluble in water, alcohol and glycerine, insoluble in acetone or diethyl ether. Sodium Hydroxide may be used in acid neutralizing, discoloring, and deodorizing.

Possible Side Effects of Sodium Hydroxide E524

Sodium Hydroxide E524 is generally considered a safe ingredient. The commonly reported side-effects of Sodium Hydroxide are rash, hives, difficulty breathing, tightness in the chest, and swelling of the mouth.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium Hydroxide is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sodium Hydroxide populations. Better consult to your doctor if you would like to intake Sodium Hydroxide E524.

Related Research

1. Theoretical simulation of reduction mechanism of graphene oxide in sodium hydroxide solution. [Phys Chem Chem Phys. 2014 Jul 7] Author: Chen C, Kong W, Duan HM, Zhang J.

2. [Conservative treatment improved corrosive esophagitis and pneumomediastinum in a patient who ingested bleaching agent containing sodium hypochlorite and sodium hydroxide]. [Chudoku Kenkyu. 2014 Mar] Author: Nakano H, Iseki K, Ozawa A, Tominaga A, Sadahiro R, Otani K.

3. Milk production is unaffected by replacing barley or sodium hydroxide wheat with maize cob silage in rations for dairy cows. [Animal. 2014 May] Author: Hymøller L, Hellwing AL, Lund P, Weisbjerg MR.

4. Ethanol production via simultaneous saccharification and fermentation of sodium hydroxidetreated corn stover using Phanerochaete chrysosporium and Gloeophyllum trabeum. [Bioresour Technol. 2014 Apr] Author: Vincent M, Pometto AL 3rd, van Leeuwen JH.

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Sodium Bicarbonate Side Effects

Sodium Bicarbonate E500 is a chemical compound with the formula NaHCO3. It is a salt composed of sodium ions and bicarbonate ions. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Sodium Bicarbonate E500?

Sodium Bicarbonate E500, known as baking soda, is a chemical leavening agent. This product appears as a white powder with a salty aroma. It reacts with acidic components in batters, releasing carbon dioxide which causes expansion in the batter and forms grainy texture in applications like pancakes, quick bread or fried foods.

Possible Side Effects of Sodium Bicarbonate E500

Sodium Bicarbonate E500 is generally considered a safe ingredient. The side effects may:

  • Frequent urge to urinate
  • headache (continuing)
  • loss of appetite (continuing)
  • mood or mental changes
  • muscle pain or twitching
  • nausea or vomiting
  • nervousness or restlessness
  • slow breathing
  • swelling of feet or lower legs
  • unpleasant taste
  • unusual tiredness or weakness

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium Bicarbonate E500 is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sodium Bicarbonate populations. Better consult to your doctor if you would like to intake Sodium Bicarbonate.

Related Research

1. Sodium acetate as a replacement for sodium bicarbonate in medical toxicology: a review. [J Med Toxicol. 2013 Sep] Author: Neavyn MJ, Boyer EW, Bird SB, Babu KM.

2. Oral prostaglandin e1 in combination with sodium bicarbonate and normal saline in the prevention of contrast-induced nephropathy: a pilot study. [Int J Angiol. 2011 Dec] Author: Franz RW, Hinze SS, Knapp ED, Jenkins JJ 2nd.

3. Effects of caffeine, sodium bicarbonate, and their combined ingestion on high-intensity cycling performance. [Int J Sport Nutr Exerc Metab. 2012 Jun] Author: Kilding AE, Overton C, Gleave J.

4. Dimethyl sulfoxide and sodium bicarbonate in the treatment of refractory cancer pain. [J Pain Palliat Care Pharmacother. 2011] Author: Hoang BX, Tran DM, Tran HQ, Nguyen PT, Pham TD, Dang HV, Ha TV, Tran HD, Hoang C, Luong KN, Shaw DG.

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