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Ethyl Acetate Side Effects

Ethyl Acetate E1504 is a transparent liquid with a fragrant odor used as an edible spice or applied to wine. It is often used in decaffeinated teas and coffees. Though Ethyl Acetate E1504 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Ethyl Acetate E1504?

Ethyl Acetate E1504 is the organic compound with the formula CH3-COO-CH2-CH3. This colorless liquid has a characteristic sweet smell similar to pears drops. It is often used primarily as a solvent and diluent, being favored because of its low cost, low toxicity, and agreeable odor. This product is commonly used in decaffeinated teas and coffees

Possible Side Effects of Ethyl Acetate E1504

Ethyl Acetate E1504 is generally considered a safe ingredient. The side effects may: Cancer, Weakness, Sexual Dysfunction, Allergy, Headache, Seizures.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Ethyl Acetate Ethyl Acetate E1504 is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Ethyl Acetate populations. Better consult to your doctor if you would like to intake Ethyl Acetate.

 

 

 

Related Research

1. Biochemical and hematological effects of acute and sub-acute administration to ethyl acetate fraction from the stem bark Scutia buxifolia Reissek in mice. [J Ethnopharmacol. 2014 May 14] Author: da Silva AR, Moreira Lda R, Brum Eda S, de Freitas ML, Boligon AA, Athayde ML, Roman SS, Mazzanti CM, Brandão R.

2. Effects of Heracleum persicum ethyl acetate extract on the growth, hyphal ultrastructure and aflatoxin biosynthesis in Aspergillus parasiticus. [Mycotoxin Res. 2013 Nov] Author: Razzaghi-Abyaneh M, Saberi R, Sharifan A, Rezaee MB, Seifili R, Hosseini SI, Shams-Ghahfarokhi M, Nikkhah M, Saberi I, Amani A.

3. Validation of an efficient method for the determination of pesticide residues in fruits and vegetables using ethyl acetate for extraction. [J Environ Sci Health B. 2007 Jun-Jul] Author: Aysal P, Ambrus A, Lehotay SJ, Cannavan A.

4. A phase I study of ethyl acetate extract of the chinese antirheumatic herb Tripterygium wilfordii hook F in rheumatoid arthritis. [J Rheumatol. 2001 Oct] Author: Tao X, Cush JJ, Garret M, Lipsky PE.

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Taurine Side Effects

Taurine is supplied as white crystals or white crystalline powder. It is commonly used in energy drinks. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Taurine?

Taurine is a white crystal powder that is odorless and tastes slightly acidic. It is a kind of amino acid with sulfur in the body of the non-protein element. Taurine helps promote infant brain and intelligence development. This product is used in infant formulas and energy drinks, and it also helps prevent cardiovascular disease, improve memory function and resist the outside environment skin invasion.

Possible Side Effects of Taurine

Taurine is generally considered a safe ingredient. Taurine is a conditional amino acid, meaning it can be manufactured naturally by our bodies, means that side effects are minimal as it is a natural substance. It is important, however, not to overuse Taurine as a supplement. The side effects may:Negative Nitrogen Balance, Drug Interactions

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Taurine is considered safe by FDA.

Suggested Dosage

Taurine is recommended to use between 1-2g in supplement form, which is adequate for the desired effects as mentioned previously.

Excess Taurine is excreted from the body by the kidneys, and there is little evidence from research conducted to show that an excessive intake of Taurine can cause any form of toxicity.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Taurine populations. Better consult to your doctor if you would like to intake Taurine.

 

 

Related Research

1. Taurine postponed the replicative senescence of rat bone marrow-derived multipotent stromal cells in vitro. [Mol Cell Biochem. 2012 Jul] Author: Ji H, Zhao G, Luo J, Zhao X, Zhang M.

2. Evaluation of potential synergistic action of a combined treatment with alpha-methyl-prednisolone and taurine on the mdx mouse model of Duchenne muscular dystrophy. [Neuropathol Appl Neurobiol. 2011 Apr] Author: Cozzoli A, Rolland JF, Capogrosso RF, Sblendorio VT, Longo V, Simonetti S, Nico B, De Luca A.

3. Combined administration of taurine and monoisoamyl DMSA protects arsenic induced oxidative injury in rats. [Oxid Med Cell Longev. 2008 Oct-Dec] Author: Flora SJ, Chouhan S, Kannan GM, Mittal M, Swarnkar H.

4. Risk assessment for the amino acids taurine, L-glutamine and L-arginine. [Regul Toxicol Pharmacol. 2008 Apr] Author: Shao A, Hathcock JN.

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L-Valine Side Effects

L-Valine is an amino acid used as food or dietary supplements. It is a branched chain amino acid, widely used in the production of pharmaceutical, food and condiment, cosmetic and medical applications. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Valine?

L-Valine  known an amino acid & a branched-chain amino acid member found in high concentration in the muscles. It has a stimulating effect and is needed for muscle metabolism, repair and growth of tissue and maintaining the nitrogen balance in the body. Since it is a branched-chain amino acid, it can be used as an energy source in the muscles, and in doing so preserves the use of glucose.

Possible Side Effects of L-Valine

L-Valine is generally considered a safe ingredient. The side effects may: with liver and/or kidney disease should not take this supplement. It should not be consumed in excess, as it can cause even hallucinations in severe cases.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Valine is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Valine populations. Better consult to your doctor if you would like to intake L-Valine.

Related Research

1. Application of metabolic engineering for the biotechnological production of L-valine. [Appl Microbiol Biotechnol. 2014 Jul] Author: Oldiges M, Eikmanns BJ, Blombach B.

2. Conformation of dehydropentapeptides containing four achiral amino acid residues – controlling the role of L-valine. [Beilstein J Org Chem. 2014 Mar 14] Author: Jewgiński M, Krzciuk-Gula J, Makowski M, Latajka R, Kafarski P.

3. Ruthenium-nitrosyl complexes with glycine, L-alanine, L-valine, L-proline, D-proline, L-serine, L-threonine, and L-tyrosine: synthesis, X-ray diffraction structures, spectroscopic and electrochemical properties, and antiproliferative activity. [Inorg Chem. 2014 Mar 3] Author: Rathgeb A, Böhm A, Novak MS, Gavriluta A, Dömötör O, Tommasino JB, Enyedy EA, Shova S, Meier S, Jakupec MA, Luneau D, Arion VB.

4. Application of a genetically encoded biosensor for live cell imaging of L-valine production in pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum strains. [PLoS One. 2014 Jan 17] Author: Mustafi N, Grünberger A, Mahr R, Helfrich S, Nöh K, Blombach B, Kohlheyer D, Frunzke J.

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L-Ornithine HCl Side Effects

L-Ornithine HCl is an amino acid. This product appears as a white crystalline powder. It can be used as a dietary and nutritional supplement. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Ornithine HCl?

L-Ornithine HCL is an amino acid which used as a supplement. It is used by athletes and bodybuilders to improve athletic performance and reduces glutamine poisoning caused by hepatic encephalopathy. It is also useful in wound healing.

Possible Side Effects of L-Ornithine HCl

L-Ornithine HCl is generally considered a safe ingredient. The side effects may: gastric upset, restlessness and insomnia. The side effects of L-Ornithine HCl supplement tend to be mild, and there are no known long-term effects. However, anyone who is pregnant, lactating or taking medications that may react with this amino acid should not consume it.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Ornithine HCl is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Ornithine HCl populations. Better consult to your doctor if you would like to intake L-Ornithine HCl.

 

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L-Isoleucine Side Effects

Isoleucine is a branched chain amino acid (BCAA) and by default also an essential amino acid (EAA). Isoleucine is important for protein synthesis and other anabolic and anti-catabolic processes in the body. Isoleucine is best taken together with the other BCAAs or leucine and valine. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Isoleucine?

L-Isoleucine is an essential amino acid, which means that humans cannot synthesize it, so it must be ingested. It appears as a white crystalline powder. Foods that have high amounts of L-Isoleucineinclude eggs, soy protein, seaweed, turkey, chicken, lamb, cheese, and fish. This product is often used as a food additive and nutrient in dietary supplements.

Possible Side Effects of L-Isoleucine

L-Isoleucine is generally considered a safe ingredient. The side effects may: Intake of Isoleucine can lead to nausea. Large doses can result in a stomach upset and indigestion.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Isoleucine is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Isoleucine populations. Better consult to your doctor if you would like to intake L-Isoleucine.

 

 

 

Related Research

1. Local rhamnosoft, ceramides and L-isoleucine in atopic eczema: a randomized, placebo controlled trial. [Pediatr Allergy Immunol. 2014 May] Author: Marseglia A, Licari A, Agostinis F, Barcella A, Bonamonte D, Puviani M, Milani M, Marseglia G.

2. Reductive amination by recombinant Escherichia coli: whole cell biotransformation of 2-keto-3-methylvalerate to L-isoleucine. [J Biotechnol. 2013 Nov] Author: Lorenz E, Klatte S, Wendisch VF.

3. L-Leucine and L-isoleucine enhance growth of BBN-induced urothelial tumors in the rat bladder by modulating expression of amino acid transporters and tumorigenesis-associated genes. [Food Chem Toxicol. 2013 Sep] Author: Xie XL, Kakehashi A, Wei M, Yamano S, Takeshita M, Yunoki T, Wanibuchi H.

4. Rational design of Escherichia coli for L-isoleucine production. [ACS Synth Biol. 2012 Nov 16] Author: Park JH, Oh JE, Lee KH, Kim JY, Lee SY.

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L-Glutamine Side Effects

L-Glutamine is an amino acid used to help synthesize proteins. It is supplied as white crystals/crystalline powder, and may be used in dietary supplements. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Glutamine?

L-Glutamine is an important amino acid that builds protein in the body. This product appears as a crystalline powder, and it can be used as a dietary supplement to cure gastric and duodenal ulcer, gastritis, and hyperchlorhydria. It is important for maintaining the suppression, structure and function of the small intestine.

Possible Side Effects of L-Glutamine

L-Glutamine is generally considered a safe ingredient. The side effects may:

  • Blood in urine
  • changes in skin color
  • chills
  • cold hands and feet
  • confusion
  • cough
  • difficulty swallowing
  • dizziness
  • fainting
  • fast heartbeat
  • fever
  • frequent and painful urination
  • headache
  • hives
  • itching
  • lightheadedness
  • lower back or side pain
  • pain, redness, or swelling in arm or leg
  • puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
  • rapid, shallow breathing
  • shortness of breath
  • skin rash
  • stomach pain
  • sudden decrease in amount of urine
  • tightness in chest
  • unusual tiredness or weakness
  • wheezing

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Glutamine is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Glutamine populations. Better consult to your doctor if you would like to intake L-Glutamine.

 

 

Related Research

1. Risk assessment for the amino acids taurine, L-glutamine and L-arginine. [Regul Toxicol Pharmacol. 2008 Apr] Author: Shao A, Hathcock JN.

2. L-Glutamine Supplementations Enhance Liver Glutamine-Glutathione Axis and Heat Shock Factor-1 Expression in Endurance-Exercise Trained Rats. [Int J Sport Nutr Exerc Metab. 2014 Sep 8] Author: Petry ER, Cruzat VF, Heck TG, Homem de Bittencourt PI Jr, Tirapegui J.

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L-Citrulline DL-Malate Side Effects

L-Citrulline Malate is a blend of L-Citrulline and Malate; a salt of Malic Acid. Citrulline Malate is an amino acid derived from watermelon that appears as a white to off-white crystalline powder. Citrulline Malate can reduce muscle fatigue and detox muscle tissue by removing ammonia. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Glutamine?

L-Citrulline DL-Malate is used as either a 2:1 or 1:1 ratio. 2:1 provides a higher ratio of L-Citrulline to Malate than 1:1 and generally costs more. The malic acid component of L-Citrulline Malate has been proven to combat fatigue and promote ATP production (ATP provides energy needed by your body for muscle contractions) while L-Citrulline alone, has not.

Possible Side Effects of Citrulline Malate

L-Citrulline DL-Malate is generally considered a safe ingredient. Research and anecdotal reports show citrulline malate isn’t strongly associated with any side effects.  This is because citrulline malate is a combination of the amino acid citrulline and the natural chemical malic acid, both of which are safe to use regularly. A few participants in one study reported slight stomach discomfort after taking citrulline malate. Even so, less than 15% of the participants reported this side effect. And, in other citrulline malate studies, no side effects were reported. At least for now, it seems citrulline malate is one ingredient you can take without expecting major negative side effects. That quality certainly sets citrulline malate apart from many other ingredients, so it’s no wonder citrulline malate is the go-to supplement for athletes and bodybuilders.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Citrulline DL-Malate is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Citrulline DL-Malate populations. Better consult to your doctor if you would like to intake L-Citrulline DL-Malate.

 

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L-Citrulline Side Effects

L-Citrulline is used as a sports performance and cardiovascular health supplement. L-Citrulline supplementation results in reduced fatigue and improved endurance for both aerobic and anaerobic prolonged exercise. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Citrulline?

L-Citrulline is a non-essential amino acid that acts as an intermediate in the urea cycle, functioning along with Arginine and Ornithine to rid the body of ammonia. It is commonly used for heart disease, body building, increasing energy, and for improving athletic performance.

Possible Side Effects of L-Citrulline

L-Citrulline is generally considered a safe ingredient. The side effects may:

By dilating blood vessels and increasing nitric oxide, L-citrulline actually lowers overall blood pressure. While this can be helpful for users with prehypertension, some people already have low blood pressure, and further reduction can be harmful.

Another possible risk of L-citrulline is its effects on the kidneys. While it doesn’t cause direct harm, L-citrulline can increase overall creatine levels.

Creatine is widely taken to boost muscle recovery, but research shows that for some, too much creatine can actually harm kidney function or cause upset stomach. If you have low blood pressure or a condition affecting the kidneys, L-citrulline could cause serious problems. Your doctor can help you make the correct choices about usage or suggest an alternative.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Citrulline is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Citrulline populations. Better consult to your doctor if you would like to intake L-Citrulline.

 

 

Related Research

1. [The role of L-arginine and L-citrulline on atherosclerosis]. [Seikagaku. 2014 Jun] Author: Hayashi T.

2. l-Citrulline, But Not l-Arginine, Prevents Diabetes Mellitus-Induced Glomerular Hyperfiltration and Proteinuria in Rat. [Hypertension. 2014 May 27.] Author: Persson P, Fasching A, Teerlink T, Hansell P, Palm F.

3. L-citrulline provides a novel strategy for treating chronic pulmonary hypertension in newborn infants. [Acta Paediatr. 2014 May 26] Author: Fike CD, Summar M, Aschner JL.

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Inosine Side Effects

Inosine is an amino acid that is a kind of coenzyme drug widely used in the medicine and the food industry. Inosine appears as a white crystalline powder, and is often used in fitness supplements for metabolism. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Inosine?

Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond. The most common use of inosine as a health supplement is the improvement of athletic performance. It is also used for its antioxidant properties and to support the nervous system.

Possible Side Effects of Inosine

Inosine is generally considered a safe ingredient. The side effects may: Although no side effects have been reported with the use of inosine, long-term use should be avoided. A very preliminary double-blind crossover study that enrolled 7 participants suggests that high doses of inosine (5,000 to 10,000 mg per day for 5 to 10 days) may increase the risk of uric acid–related problems, such as gout or kidney stones. The safety of inosine for young children, pregnant or nursing women, or those with serious liver or kidney disease has not been established.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Inosine is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Inosine populations. Better consult to your doctor if you would like to intake Inosine.

 

 

Related Research

1. Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial. [JAMA Neurol. 2014 Feb] Author: Parkinson Study Group SURE-PD Investigators, Schwarzschild MA, Ascherio A, Beal MF, Cudkowicz ME, Curhan GC, Hare JM, Hooper DC, Kieburtz KD, Macklin EA, Oakes D, Rudolph A, Shoulson I, Tennis MK, Espay AJ, Gartner M, Hung A, Bwala G, Lenehan R, Encarnacion E, Ainslie M, Castillo R, Togasaki D, Barles G, Friedman JH, Niles L, Carter JH, Murray M, Goetz CG, Jaglin J, Ahmed A, Russell DS, Cotto C, Goudreau JL, Russell D, Parashos SA, Ede P, Saint-Hilaire MH, Thomas CA, James R, Stacy MA, Johnson J, Gauger L, Antonelle de Marcaida J, Thurlow S, Isaacson SH, Carvajal L, Rao J, Cook M, Hope-Porche C, McClurg L, Grasso DL, Logan R, Orme C, Ross T, Brocht AF, Constantinescu R, Sharma S, Venuto C, Weber J, Eaton K.

2. Inosine enhances axon sprouting and motor recovery after spinal cord injury. [PLoS One. 2013 Dec 2] Author: Kim D, Zai L, Liang P, Schaffling C, Ahlborn D, Benowitz LI.

3. Boosting endogenous neuroprotection in multiple sclerosis: the ASsociation of Inosine and Interferon beta in relapsing- remitting Multiple Sclerosis (ASIIMS) trial. [Mult Scler. 2010 Apr] Author: Gonsette RE, Sindic C, D’hooghe MB, De Deyn PP, Medaer R, Michotte A, Seeldrayers P, Guillaume D; ASIIMS study group.

4. Inosine improves islet xenograft survival in immunocompetent diabetic mice. [Eur J Med Res. 2005 Jul 29] Author: Schneider S, Klein HH.

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Glycine Side Effects

Glycine E640 is a white crystalline powder with a sweet taste. It is often used as a flavoring or a sweetener in combination with DL-alanine or Citric acid. Glycine is used in alcoholic beverages, peanut jams, and edible salt and vinegar. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Glycine E640?

Glycine E640 is a white crystalline powder that is odorless and has a peculiar sweetness. Food grade Glycine E640 is mainly used as a nutritional supplement and food additive. It is also used in alcoholic beverages as an acid corrector or buffer for the composition of wine and soft beverage. Glycine E640 is used as an additive for the making of salted vegetables and sweet jams, sauces, vinegar and fruit juice. This product functions as a stabilizer for cream cheese, margarine, fast cooked noodles, white flour and pig lard.

Possible Side Effects of Glycine E640

Glycine E640 is generally considered a safe ingredient. The side effects may: nausea, vomiting, upper digestive tract discomfort, and mild drowsiness. However, potentially serious side effects of glycine can also occur. Contact your healthcare provider if you have symptoms of schizophrenia that are getting worse or develop signs of an allergic reaction while taking glycine supplements.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Glycine E640 is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Glycine populations. Better consult to your doctor if you would like to intake Glycine.

 

 

Related Research

1. [Augmentation of antipsychotics with glycine may ameliorate depressive and extrapyramidal symptoms in schizophrenic patients–a preliminary 10-week open-label study]. [Psychiatr Pol. 2013 Jul-Aug] Author: Strzelecki D, Kropiwnicki P, Rabe-Jabłońska J.

2. Glycine administration attenuates skeletal muscle wasting in a mouse model of cancer cachexia. [Clin Nutr. 2014 Jun] Author: Ham DJ, Murphy KT, Chee A, Lynch GS, Koopman R.

3. [Changes in positive and negative symptoms, general psychopathology in schizophrenic patients during augmentation of antipsychotics with glycine: a preliminary 10-week open-label study]. [Psychiatr Pol. 2011 Nov-Dec] Author: Strzelecki D, Rabe-Jabłońska J.

4. Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models. [Pharmacol Rep. 2010 Mar-Apr] Author: Socała K, Nieoczym D, Rundfeldt C, Wlaź P.

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DL Aspartic Acid Side Effects

DL-Aspartic Acid is a white crystalline powder that is odorless with a slightly acidic taste. It is soluble in acid and is insoluble in alcohol. DL-Aspartic Acid can be added to drinks as a nutritional supplement and can be used in medicine as an ammonia detoxicating agent. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is DL-Aspartic Acid?

DL-Aspartic Acid is a colorless or white odorless crystal with the molecular formula (C4H7NO2) and a sour taste. Difficult to dissolve in water and insoluble in ethanol and ether. DL-aspartic acid is used in amino acid transfusion, synthetic drugs and cosmetics. It can be used as nutritional supplement and can be added into kinds of drinks. Additionally it can be used in treatment of liver trouble and heart disease

Possible Side Effects of DL-Aspartic Acid

DL-Aspartic Acid is generally considered a safe ingredient. The side effects may:

  • Acne;
  • Nausea and/or vomiting;
  • Irritability, depression and/or mood changes;
  • Diarrhea;
  • Headache.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. DL-Aspartic Acid is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to DL-Aspartic Acid populations. Better consult to your doctor if you would like to intake DL-Aspartic Acid.

 

Related Research

1. DL-Aspartic acid administration improves semen quality in rabbit bucks. [Anim Reprod Sci. 2010 Apr] Author: Macchia G, Topo E, Mangano N, D’Aniello E, Boni R.

2. Infrared and laser Raman spectral studies of bis(dl-aspartic acid) sulfate. [Spectrochim Acta A Mol Biomol Spectrosc. 2005 Nov] Author: Mary MB, Ramakrishnan V.

3. Neutron reflectivity and external reflection FTIR studies of DL-aspartic acid crystallization beneath nylon 6 spread films. [Langmuir. 2004 Apr 27] Author: Jamieson MJ, Cooper SJ, Miller AF, Holt SA.

4. [Protective effect of poly DL-aspartic acid on ototoxicity of gentamicin]. [Zhonghua Er Bi Yan Hou Ke Za Zhi. 1999 Aug] Author: Guo Y, Li Z, Hu M.

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D-Aspartic Acid Side Effects

Aspartic acid, also known as aspartate, is an α-amino acid that is used in the biosynthesis of proteins. Similar to all other amino acids it contains an amino group and a carboxylic acid. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is D-Aspartic Acid?

D-Aspartic Acid is a White or white crystalline powder with the molecular formula (C4H7NO2). Primarily used as a nutraceutical, it is considered to be a nutrition enhancer and can be found in many nutritional supplements or as an additive in many foods.

Possible Side Effects of D-Aspartic Acid

D-Aspartic Acid is generally considered a safe ingredient. The side effects may:

  • Acne
  • Headache
  • Diarrhea
  • Mood Swings
  • Depression

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. D-Aspartic Acid is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to D-Aspartic Acid populations. Better consult to your doctor if you would like to intake D-Aspartic Acid.

 

 

Related Research

1. D-aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men. [Nutr Res. 2013 Oct] Author: Willoughby DS, Leutholtz B.

2. Decreased levels of free D-aspartic acid in the forebrain of serine racemase (Srr) knock-out mice. [Neurochem Int. 2013 May] Author: Horio M, Ishima T, Fujita Y, Inoue R, Mori H, Hashimoto K.

3. Gender differences in D-aspartic acid content in skull bone. [Hiroshima J Med Sci. 2012 Dec] Author: Torikoshi-Hatano A, Namera A, Shiraishi H, Arima Y, Toubou H, Ezaki J, Morikawa M, Nagao M.

4. D-Aspartic acid implication in the modulation of frog brain sex steroid levels. [Gen Comp Endocrinol. 2013 Jan 15] Author: Santillo A, Pinelli C, Burrone L, Chieffi Baccari G, Di Fiore MM.

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Betaine Monohydrate Side Effects

Betaine Monohydrate is a white crystalline powder used as a food additive to improve the quality of meat and provide enhanced stability for micronutrients such as vitamins A and B. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Betaine Monohydrate?

Betaine (Trimethylglycine) is an amino acid. It is found in quinoa, spinach, wheat bran, lamb, and beets. It is essential for the functions of brain chemistry, and it helps protect the body from dehydration.Betaine (Trimethylglycine) supplements are manufactured as a byproduct of sugar beet processing.

Possible Side Effects of Betaine Monohydrate

Betaine is generally considered a safe ingredient. The side effects may:

  • Diarrhea
  • nausea
  • stomach upset

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Betaine Monohydrate is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Betaine Monohydrate populations. Better consult to your doctor if you would like to intake Betaine Monohydrate.

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Betaine Side Effects

Betaine is a white crystalline powder used as a food additive to improve the quality of meat and provide enhanced stability for micronutrients such as vitamins A and B. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Betaine?

Betaine (Trimethylglycine) is an amino acid. It is found in quinoa, spinach, wheat bran, lamb, and beets. It is essential for the functions of brain chemistry, and it helps protect the body from dehydration.Betaine (Trimethylglycine) supplements are manufactured as a byproduct of sugar beet processing.

Possible Side Effects of Betaine

Betaine is generally considered a safe ingredient. The side effects may:

  • Diarrhea
  • nausea
  • stomach upset

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Betaine is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Betaine populations. Better consult to your doctor if you would like to intake Betaine.

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Hordenine HCl Side Effects

Hordenine HCl is used as a dietary supplement. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Hordenine HCl?

Hordenine HCL is an alkaloid of the phenethylamine, used as supplement. Hordenine is best known as a central nervous stimulant that assists in weight loss in sports nutriton supplements.

Possible Side Effects of Hordenine HCl

Hordenine HCl is generally recognised as safe, possible side effects of hordenine that have been reported are nausea, insomnia, dizziness, anxiety, upset stomach, mood swings, and rapid heart rate.

GRAS Affirmation: No

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Hordenine HCl is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Methylsulfonylmethane populations. Better consult to your doctor if you would like to intake Hordenine HCl.

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