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Ester Gum Side Effects

Ester gum, is also known as Glycerol ester of wood rosin, is an oil-soluble food additive (E number E445). The food-grade material is used in foods, beverages, and cosmetics to keep oils in suspension in water. It is also used as an ingredient in the production of chewing-gum and ice cream. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Ester gum?

Ester Gum (Glycerol Esters of Wood Rosin) is a food additive that is used as an emulsifier and stabilizer, to keep oils in suspension in water. This product appears as a yellow to amber hard rosin. It serves as a natural alternative to brominated vegetable oil, particularly in citrus-flavored soft drinks.

Possible Side Effects of Ester gum

Although Ester gum generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Ester Gum allergy.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Ester gum is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Ester gum populations. Better consult to your doctor if you would like to intake Ester gum.

Related Research

1. Allergic lipstick cheilitis due to ester gum and ricinoleic acid. [Contact Dermatitis. 1998 Jul] Author: Inoue A, Shoji A, Aso S.

2. Genotoxicity studies of the food additive ester gum. [Food Chem Toxicol. 1992 Jul] Author: Mukherjee A, Agarwal K, Chakrabarti J.

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Kojic Acid Side Effects

Kojic acid is used in food and cosmetics to preserve or change colors of substances. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Kojic Acid?

Kojic Acid is an off-white crystalline powder with a purity of 99%. This product is great for skin care because it can add shine and remove spots. Kojic acid can act as anti-oxidant, antiseptic, and preservative. This product can be used in food or cosmetics to preserve or change colors of substance. Kojic acid is used in a variety of ways like, preserving colors in seafood, preventing browning of cut fruits, and as a by-product in the manufacturing of rice wine.

Possible Side Effects of Kojic Acid

Although Kojic Acid generally regarded as a very safe and effective supplement, there can be some minor side effects. The common side effects is Skin Sensitivity.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Kojic Acid is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Kojic Acid populations. Better consult to your doctor if you would like to intake Kojic Acid.

Related Research

1. Final report of the safety assessment of Kojic acid as used in cosmetics. [Int J Toxicol. 2010 Nov-Dec] Author: Burnett CL, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA.

2. Kojic acid -absence of tumor-initiating activity in rat liver, and of carcinogenic and photo-genotoxic potential in mouse skin. [J Toxicol Sci. 2007 May] Author: Higa Y, Kawabe M, Nabae K, Toda Y, Kitamoto S, Hara T, Tanaka N, Kariya K, Takahashi M.

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ButylParaben Side Effects

Butylparaben, or butyl p-hydroxybenzoate, It is a white solid that is soluble in organic solvents. It has proven to be a highly successful antimicrobial preservative in cosmetics. Butylparaben is also used in medication suspensions, and as a flavoring additive in food. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Butylparaben?

Butylparaben (Butyl P-Hydroxybenzoate) is a white crystalline powder with a particular odor and is easily dissolved in alcohol, ether, chloroform, but difficult to dissolve in water. It is used as both an antiseptic and flavoring agent in food. It can also be used as an antifungal agent in bread, because it is particularly active against molds and yeasts, and less active against bacteria.

Possible Side Effects of Butylparaben

Although Butylparaben generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may: Cancer, Allergy, Irritability, Tumors, Acne, Dry Skin, Rash, Hair Loss, Itching, Weakness.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Butylparaben is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Butylparaben populations. Better consult to your doctor if you would like to intake Butylparaben.

 

 

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EthylParaben Side Effects

Ethylparaben E214 (ethyl para-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid. Its formula is HO-C6H4-CO-O-CH2CH3. It is a member of the class of compounds known as parabens. It is used as an antifungal preservative. As a food additive, it has E number E214. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is EthylParaben E214?

Ethylparaben E214 is a paraben and preservative found in many skin care products, ranging from skin cream to body lotion to deodorant. It can be found in essential oils used to treat dry skin and in primrose oil serving as an anti-septic.

Possible Side Effects of EthylParaben E214

Although EthylParaben E214 generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Breast Cancer 

    Early Puberty

    Decreased Sperm Levels

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. EthylParaben E214 is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to EthylParaben E214 populations. Better consult to your doctor if you would like to intake EthylParaben E214.

 

 

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Silicon Dioxide Side Effects

Silicon dioxide E551, also known as silica (from the Latin silex), is a chemical compound that is an oxide of silicon with the chemical formula SiO2.  Though Silicon dioxide E551 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Silicon Dioxide E551?

Silicon Dioxide E551 is an oxide of silicon with the chemical formula SiO2. This product is a common additive in the production of foods, where it is used primarily as a flow agent in powdered foods, or to absorb water in hygroscopic applications. It is often used in cheese, fat spreads, confectionery, dried vegetables, etc.

Possible Side Effects of Silicon Dioxide E551

Although Silicon Dioxide E551 generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Kidney stones can occur, though rarely, in people taking silicon-containing antacids for long periods of time.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Silicon Dioxide is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Silicon Dioxide populations. Better consult to your doctor if you would like to intake Silicon Dioxide.

 

 

 

Related Research

1. Oxidative potential of ultraviolet-A irradiated or nonirradiated suspensions of titanium dioxide or silicon dioxide nanoparticles on Allium cepa roots. [Environ Toxicol Chem. 2014 Apr] Author: Koce JD, Drobne D, Klančnik K, Makovec D, Novak S, Hočevar M.

2. Acute toxicity of intravenously administered microfabricated silicon dioxide drug delivery particles in mice: preliminary findings. [Drugs R D. 2005] Author: Martin FJ, Melnik K, West T, Shapiro J, Cohen M, Boiarski AA, Ferrari M.

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Xylitol Side Effects

Xylitol E967 is a sugar alcohol used as a sweetener. Xylitol E967 is categorized as a polyalcohol or sugar alcohol. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Xylitol E967?

Xylitol E967 is a white crystalline powder. It is a natural sweetener made from corncob or sugar cane bagasse but its sweetness level equals that of sucrose. Xylitol is found in berries, oats, and mushrooms and is used in foods, medicine and light industries. It is an intermediate that regularly operate on the glucose metabolism in human body. It can supply liver glycogen and improves liver function, so xylitol is ideal for use in the resuscitation of patients from diabetic and hepatic coma. It also has the function of tooth-decay prevention.

Possible Side Effects of Xylitol E967

Although Xylitol generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Xylitol E967 is basically used for oral health. It is an alcohol basically and if the alcohol is not digested, it can lead to gastric and diarrhea. If your intake of xylitol is very high it may lead to hypoglycemia or low blood sugar.Xylitol E967 can have laxative effects, if consumed in large doses. Diarrhea and gas are common side effects of xylitol. Very high doses of xylitol given in IV is known to cause high uric acid levels in blood. These high levels of uric acid can cause kidney stones. There are chances of changes in liver function tests and high level of blood acidity.

    In case of substandard purification techniques used for xylitol extracted from birch trees, they may cause very rare cases of allergies in people. In case of allergic reaction, the symptoms include itching, hives, skin rash, wheezing, breathing difficulty and swelling in mouth and throat. These allergies are very, very rare instances of xylitol side effects.

    Xylitol E967 is considered safe for humans, but in case of dogs, it is exactly the opposite. One should avoid giving any xylitol containing product to the dog. It can lead to hypoglycemia, seizures and collapse of dog after consumption of large quantity of xylitol. It promotes release of insulin and thus leads to severe hypoglycemia in dogs. It can even lead to liver damage in dogs.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Xylitol is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Xylitol populations. Better consult to your doctor if you would like to intake Xylitol.

 

 

 

Related Research

1. Xylitol; A review on Bio-production, Application, Health Benefits and Related Safety Issues. [Crit Rev Food Sci Nutr. 2013 Oct] Author: Ur-Rehman S, Mushtaq Z, Zahoor T, Jamil A, Anjum Murtaza M.

2. Xylitol toxicosis in dogs. [Vet Clin North Am Small Anim Pract. 2012 Mar] Author: Murphy LA, Coleman AE.

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Sucralose Side Effects

Sucralose Side Effects

Sucralose is a artificial sweetener with zero calorie used in sugar-free products. Though it’s considered safe by the Food and Drug Administration (FDA), some are convinced it has potentially dangerous health effects.

What Is It?

Sucralose, CAS number 56038-13-2, E number E955, used as food sweetener, it is about 600 times as sweet as sucrose. Sucralose accepted as safe food sweetener in many food products. Sucralose is a artificial sweetener manufactured through chemical synthesis, available as white powder and granular. Sucralose is used in chewing gum, fruit spreads, jams, processed fruit, processed vegetables, candy, beverages, coffee, tea and salad dressing.

Possible Side Effects of Sucralose

# Releases toxins: sucralose can releases potentially toxic compounds chloroproanols during baking.

# Change INTESTINAL Flora : “Made from sugar, taste like sugar” is the slogan promoting Sucralose to the market. Yes, the manufacturing process of Sucralose is adding chlorine to sugar, yet increasing the number of chlorine atoms. Sucralose would not be digested due to this alteration. As a result it is calorie-free. can cause bloating, gas and diarrhea. When intake in large quantities, Sucralose may have a laxative effect. High dosage of sucralose may lead to lower healthy gut bacteria levels and may affect the absorption of certain medications.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sucralose is considered safe by FDA according to existing data and granted GRAS status.

Suggested Dosage

Dosage of Sucralose in large quantity may hurt our health, please follow the guideline of using Sucralose: ADI 0-40 mg/kg
* ADI: Acceptable Daily Intake
* MTDI: maximum tolerable daily intake
* Data source: JECFA Database of WHO

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sucralose populations. As with most things for Newborns, children, pregnant, it is always best to consult with your health care provider about what artificial ingredients are safe for you to use.
Sucralose is safe and suitable for all segments of the population. There is no evidence that Sucralose could have any side effects on these vulnerable populations.

Yet, some people still believe that the use of Sucralose should be limited in infants, children, and pregnant women.

How to avoid Sucralose

By reading the labels of the foods and drinks you purchase, you should be able to identify the sweetener. It will be listed as Sucralose, according to the FDA. It could also be labeled under the brand names.

As it’s a sugar replacement sweetener, you will largely find it in sugar-free or low-sugar products. Diet sodas may be sweetened with a combination of Sucralose and other artificial sweeteners.

Related Research

1. Early Life Stage (ELS) Toxicity of Sucralose to Fathead Minnows, Pimephales promelas. [Bull Environ Contam Toxicol. 2014 Aug] Author: Stoddard KI, Huggett DB.

2. Sucralose, a synthetic organochlorine sweetener: overview of biological issues. [J Toxicol Environ Health B Crit Rev. 2013] Author: Schiffman SS, Rother KI.

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Stevioside Side Effects

Stevioside is a white crystalline powder that is 200-400 times sweeter than sucrose and is used as a low calorie sweetener in food and beverages. It is often used in cakes, cookies, pies, bakery products, and dietary supplements. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Stevioside?

Stevioside 95%-98% is a zero calorie, low-carb, sugar free, 100% natural sweetener. It has a total content of approximately 95% and a reb-A content of 20%, and it has 270 times the sweetness of sugar. It is often used in tea, soft drinks, baked goods, jams and jellies, candies, yogurts, pastries, chewing gum, etc.

Possible Side Effects of Stevioside

Although Stevioside generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • high doses of stevia may lead to serious side effects. A study showed that high doses of stevia led to a decrease in weight of testis, seminal vesicle and cauda epididymidis. Consequently, intake of high dosages of stevia may lead to the side effect of male infertility! In addition, a few studies showed that stevioside (from stevia leaves) is a vasodilator. It has insulinotropic, glucagonostatic, anti-hyperglycemic and blood pressure-lowering effects in type 2 diabetic animal models.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Stevioside is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Stevioside populations. Better consult to your doctor if you would like to intake Stevioside.

 

 

 

Related Research

1. Stevioside and related compounds – molecules of pharmaceutical promise: a critical overview. [Arch Pharm (Weinheim). 2011 Jan] Author: Brahmachari G, Mandal LC, Roy R, Mondal S, Brahmachari AK.

2. Long-term feeding effects of stevioside sweetener on some toxicological parameters of growing male rats. [J Appl Toxicol. 2011 Jul] Author: Awney HA, Massoud MI, El-Maghrabi S.

3. Daily intake assessment of saccharin, stevioside, D-sorbitol and aspartame from various processed foods in Korea. [Food Addit Contam. 2005 Nov] Author: Chung MS, Suh HJ, Yoo W, Choi SH, Cho YJ, Cho YH, Kim CJ.

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Sorbitol Side Effects

Sorbitol E420 is a clear, colorless, sugar alcohol. It functions as a humectant and sugar substitute. Sorbitol  is commonly used in shredded coconut, pet foods, candy, frozen desserts, low-calorie beverages, chewing gum, ice cream, and sugar-based confections. Though Sorbitol E420 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Sorbitol E420?

Sorbitol E420 is a low calorie sweetener that has a good taste and is anti-cariogenic. It is good for producing kinds of low calorie, low sugar and low fat products. Sorbitol is also a moisturizer and stabilizer, besides being sweet. It can be used in confectionery, bakery foods, frozen dessert, biscuit, cake, sugar-coat and chocolate. It has one third less calories than sucrose, is anti-cariogenic, and anti-crystallization.

Possible Side Effects of Sorbitol E420

Although Sorbitol E420 generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Anal irritation; diarrhea; gas; nausea; stomach cramps.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sorbitol is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sorbitol E420 populations. Better consult to your doctor if you would like to intake Sorbitol E420.

 

 

Related Research

1. Comparative study–efficacy, safety and compliance of intravenous iron sucrose and intramuscular iron sorbitol in iron deficiency anemia of pregnancy. [J Pak Med Assoc. 2002 Sep] Author: Wali A, Mushtaq A, Nilofer.

2. Pharmacokinetics, pharmacodynamics, tolerability, and safety of a novel sorbitol dehydrogenase inhibitor in healthy participants. [J Clin Pharmacol. 2010 May] Author: Landau Z, Novotny MJ, Preston GM, Wright K, Freeman T, Dai H, Thompson J, Oates PJ, Calle RA.

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Sodium Cyclamate Side Effects

Sodium Cyclamate E952 Side Effects

Sodium Cyclamate E952 is a artificial sweetener with zero calorie used in sugar-free products. It’s not considered safe by the Food and Drug Administration (FDA), and some are convinced it has potentially dangerous health effects.

What Is It?

Sodium Cyclamate, CAS number 139-05-9, E number E952, used as sweetener as it is 30–50 times sweeter than sugar. Sodium Cyclamate is a sodium salt of cyclamic acid manufactured through chemical synthesis, CP95 (flaky crystalline powder) and NF13 (needle-shaped). It is used a sugar substitute in soft drinks, liquors, seasonings, cakes, biscuits, bread, and ice cream.

Possible Side Effects of Sodium Cyclamate E952

# Cancer Risk: Rats given cyclamate may develop bladder cancer.

# Male Fertility effects: Rats had negative side effects like testicular atrophy but mice did not.  Cyclamate is composed to Cyclohexylamine, which could cause testicular atrophy in rats.

GRAS Affirmation: NOT

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements.

The U.S. Food and Drug Administration banned the use of cyclamate in 1969 due to concerns about its cancer risk in animals. The FDA has not yet to agree to use cyclamate through some research show it was safe.

Suggested Dosage

Dosage of Sodium Cyclamate E952 in large quantity may hurt our health, please follow the guideline of using Sodium Cyclamate: ADI 0-7 mg/per kilogram of body weight
* ADI: Acceptable Daily Intake
* MTDI: maximum tolerable daily intake
* Data source: JECFA Database of WHO

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sucralose populations. As with most things for Newborns, children, pregnant, it is always best to consult with your health care provider about what artificial ingredients are safe for you to use.
Sodium Cyclamate is safe and suitable for all segments of the population. There is no evidence that Sodium Cyclamate E952 could have any side effects on these vulnerable populations.

Yet, some people still believe that the use of Sodium Cyclamate E952 should be limited in infants, children, and pregnant women.

How to avoid Sodium Cyclamate E952

By reading the labels of the foods and drinks you purchase, you should be able to identify the sweetener. It will be listed as Sodium Cyclamate, according to the FDA. It could also be labeled under the brand names.

As it’s a sugar replacement sweetener, you will largely find it in sugar-free or low-sugar products. Diet sodas may be sweetened with a combination of Sodium Cyclamate and other artificial sweeteners.

Related Research

1. Rapid analysis of cyclamate in foods and beverages by gas chromatography-electron capture detector (GC-ECD). [Food Chem. 2012 Oct] Author: Yu S, Zhu B, Lv F, Li S, Huang W.

2. The safety of cyclamate–an artificial sweetener. [Med Lett Drugs Ther. 1969 Oct] Author: [No authors listed]

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Polydextrose Side Effects

Polydextrose E1200 is frequently used to increase the non-dietary fiber content of food, to replace sugar, and to reduce calories and fat content. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Polydextrose E1200?

Polydextrose E1200 is an indigestible synthetic polymer of glucose. Polydextrose E1200 is frequently used to increase the non-dietary fiber content of food, to replace sugar, and to reduce calories and fat content. This product appears as a free flowing powder, and is a multi-purpose food ingredient. It is commonly used as a humectant, stabilizer, and thickening agent in commercial beverages, cakes, candies, dessert mixes, breakfast cereals, gelatin, frozen desserts, puddings, and salad dressings.

Possible Side Effects of Polydextrose E1200

Polydextrose E1200 is generally considered a safe ingredient. Polydextrose E1200 can possible cause intestinal gas (flatulence), bloating, stomachcramps, and diarrhea.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Polydextrose is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Polydextrose E1200 populations. Better consult to your doctor if you would like to intake Polydextrose.

 

 

 

Related Research

1. Safety evaluation of polydextrose in infant formula using a suckling piglet model. [Food Chem Toxicol. 2009 Jul] Author: Herfel TM, Jacobi SK, Lin X, Walker DC, Jouni ZE, Odle J.

2. [Determination of polydextrose in food by high performance anion exchange chromatographic method with pulsed amperometric detector]. [Wei Sheng Yan Jiu. 2008 Mar] Author: Li J, Wang G, Yang Y.

3. A review of the studies of the safety of polydextrose in food. [Food Chem Toxicol. 1999 Feb-Mar] Author: Burdock GA, Flamm WG.

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Neotame Side Effects

Neotame E961 appears as a white crystalline powder that serves as an artificial sweetener that is between 7,000-13,000 times sweeter than table sugar. This product is moderately heat stable and extremely potent. Neotame E961 is used in canned fruit, jellies, soft drinks chewing gum, and as table top sweeteners. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Neotame E961?

Neotame E961 is a white powdered no-calorie sweetener, which is a derivative of the dipeptide composed of the amino acids, aspartic acid and phenylalanine. The components of neotame are joined together to form a uniquely sweet ingredient. The FDA approved the use of neotame as a general purpose sweetener in July 2002.  Neotame E961 is used in the application of canned fruit, jellies, soft drinks, bakery food, and chewing gum.

Possible Side Effects of Neotame E961

Neotame is generally considered a safe ingredient. Possible long-term side effects

  • brain damage
  • bodily tissue damage

medicine)

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Neotame E961 is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Neotame E961 populations. Better consult to your doctor if you would like to intake Neotame.

 

 

 

Related Research

1. Determination of neotame in beverages, cakes and preserved fruits by column-switching high-performance liquid chromatography. [Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010 Sep] Author: Yang D, Chen B.

2. Long-term food consumption and body weight changes in neotame safety studies are consistent with the allometric relationship observed for other sweeteners and during dietary restrictions. [Regul Toxicol Pharmacol. 2003 Oct] Author: Flamm WG, Blackburn GL, Comer CP, Mayhew DA, Stargel WW.

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Mannitol Side Effects

Mannitol E421 is used as a sweetener in chewing gum, pastries, cereal, and pressed mints. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Mannitol E421?

Mannitol E421 is a type of sugar alcohol which is also used as a medication. As a sugar, it is often used as a sweetener in diabetic food, as it is poorly absorbed from the intestines. Mannitol is a raw material that acts as an inhibitor and emulsitying agent in many fields. Mannitol is used as a food additive in yogurts, puddings, processed cheeses, baked goods, processed meats, sauces, soups, etc. Mannitol E421 is also used in the medicine industry, that can reduce intracranial pressure, prevent blood pressure from rising, and brain fever.

Possible Side Effects of Mannitol E421

Mannitol E421 is generally considered a safe ingredient. The side effects may:

  • Chest discomfort
  • cough
  • difficult or labored breathing
  • dry heaves
  • runny nose
  • shortness of breath
  • sore throat
  • tightness in the chest
  • troubled breathing
  • vomiting
  • wheezing

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Mannitol E421 is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Mannitol E421 populations. Better consult to your doctor if you would like to intake Mannitol E421.

 

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Maltitol Side Effects

Maltitol E965 is a sweetener used in functional food, confectionery and chocolate, fruit juice drinks, and frozen food.. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Maltitol E965?

Maltitol Powder E965 is a product that is produced as a white crystalline powder and is particularly used as a bulk sweetener with a sweet taste that is similar to sucrose in intensity. This product may be useful in formulating a variety of low-calorie, low-fat, and sugar-free foods. Maltitol E965 may be useful for people with diabetes, it does not raise blood glucose or insulin levels. Maltitol can be used in many fields as a sweetener, emulsifier, and stabilizer, in stuffings, biscuits, cakes, candies, chewing gums, jams, beverages, ice creams, daubed foods, and baking food, etc.

Possible Side Effects of Maltitol E965

Maltitol E965 is generally considered a safe ingredient. Common side effects may:

  • Stomach and Abdominal Pain

    Diarrhea

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Maltitol E965 is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Maltitol populations. Better consult to your doctor if you would like to intake Maltitol E965.

 

 

Related Research

1. Effects of sugar-free chewing gum sweetened with xylitol or maltitol on the development of gingivitis and plaque: a randomized clinical trial. [Int J Dent Hyg. 2014 Mar] Author: Keukenmeester R, Slot D, Rosema N, Van Loveren C, Van der Weijden G.

2. Digestive tolerance and postprandial glycaemic and insulinaemic responses after consumption of dairy desserts containing maltitol and fructo-oligosaccharides in adults. [Eur J Clin Nutr. 2014 May] Author: Respondek F, Hilpipre C, Chauveau P, Cazaubiel M, Gendre D, Maudet C, Wagner A.

3. The genotoxic and teratogenic effects of maltitol in rats. [Toxicol Ind Health. 2013 Nov] Author: Canimoglu S, Rencuzogullari E.

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Isomalt Side Effects

Isomalt E953 is a sugar substitute, a type of sugar alcohol, used primarily for its sugar-like physical properties. It has only a small impact on blood sugar levels and does not promote tooth decay, i.e. is tooth-friendly. Though Isomalt E953 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Isomalt E953?

Isomalt (Palatinitol) E953 is a natural and safe sugar replacer. Thanks to the benefits it provides natural taste, low calories, low hygroscopicity and tooth friendly. Isomalt suits all kinds of people, especially those people who are not able to eat sugar. It’s advantages will make it more important in the development of sugar free products. Isomalt shows its advantage as sweet purity, without the badness after taste, bringing the reaction with the strong sweet acidifier and conceals its bad after taste and has low moisture absorption. Isomalt can be applied in many foods, such as candy, chocolate, gum, confiture, corn breakfast food, baking food, daubing food, table sugar, low-fat milk, ice-cream and cool drinks.

Possible Side Effects of Isomalt E953

Isomalt E953 is generally considered a safe ingredient. If you are sensitive to sugar polyols, the side effect not only diarrhea, but also abdominal pain, bloating and flatulence when eating even very small amounts of isomalt E953.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Isomalt E953 is considered safe by FDA.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Isomalt populations. Better consult to your doctor if you would like to intake Isomalt.

 

 

 

Related Research

1. Frozen yogurt with added inulin and isomalt. [J Dairy Sci. 2011 Apr] Author: Isik U, Boyacioglu D, Capanoglu E, Erdil DN.

2. Effects of isomalt consumption on gastrointestinal and metabolic parameters in healthy volunteers. [Br J Nutr. 2005 Oct] Author: Gostner A, Schäffer V, Theis S, Menzel T, Lührs H, Melcher R, Schauber J, Kudlich T, Dusel G, Dorbath D, Kozianowski G, Scheppach W.

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