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Epsilon-Polylysine Side Effects

ε-Polylysine used as a natural preservative in dairy, baked products, meat products, confectionery, and convenience foods. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Epsilon-Polylysine?

ε-Polylysine is a natural substance from streptomyces albulus metabolism. It can hinder the growth of Gram-negative and Gram-positive bacteria, moulds, yeasts, etc. It is mainly used as a food preservative that is safe, highly efficient, and has no side-effects. In food application, it is usually applied with alcohol, organic acids, or glyceride, etc.. It can be used in cooked rice, cakes, snacks, noodles, drinks, brewing, meat products, canned food, etc.

Possible Side Effects of Epsilon-Polylysine

Although Epsilon-Polylysine generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Epsilon-Polylysine is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Epsilon-Polylysine populations. Better consult to your doctor if you would like to intake Epsilon-Polylysine.

 

 

 

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gamma-Aminobutyric acid Side Effects

Gamma Aminobutyric Acid (GABA) is an inhibitory neurotransmitter that is a natural non-protein amino acid. It is used as a functional food additive in beverages, chocolate, apple juice, cocoa, sugar, toast, bread and yogurt products. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Gamma Aminobutyric Acid?

Gamma-AminoButyric Acid, commonly referred to as GABA, is a vital neurotransmitter in white crystalline powder form. It offers a host of benefits, including increased brain activity and cell function, improved brain cell metabolism, prevention of dementia, significant alleviation of depression, and improved sleep quality. GABA is commonly used in nutritional supplements and pharmaceuticals or as an additive in nutritional foods and beverages.

Possible Side Effects of Gamma Aminobutyric Acid

Although Gamma Aminobutyric Acid generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • women who are pregnant or lactating should avoid taking GABA supplements. In addition, people with liver or kidney disease shouldn’t take GABA supplements without first consulting a doctor.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Gamma Aminobutyric Acid is considered safe.

Suggested Dosage

The suggested dose of GABA to be taken depends upon the condition that it aims to treat. For example, adults with high blood pressure are advised to take 10mg of GABA a day whereas users with conditions such as insomnia and anxiety, such as myself, can take higher doses of up to 1000mg a day.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Gamma Aminobutyric Acid populations. Better consult to your doctor if you would like to intake Gamma Aminobutyric Acid.

 

 

 

Related Research

1. Production of gaba (γ – Aminobutyric acid) by microorganisms: a review. [Braz J Microbiol. 2012 Oct] Author: Dhakal R, Bajpai VK, Baek KH.

2. Oral treatment with γ-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice. [PLoS One. 2011] Author: Tian J, Dang HN, Yong J, Chui WS, Dizon MP, Yaw CK, Kaufman DL.

3. Production of gamma-aminobutyric acid by Lactobacillus brevis NCL912 using fed-batch fermentation. [Microb Cell Fact. 2010 Nov 12] Author: Li H, Qiu T, Huang G, Cao Y.

4. Lactic acid bacterial cell factories for gamma-aminobutyric acid. [Amino Acids. 2010 Nov] Author: Li H, Cao Y.

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beta-Alanine Side Effects

Beta-Alanine can increase the concentration of carnosine in muscles, decrease fatigue in athletes and increase total muscular work done. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Beta-Alanine?

Beta-Alanine is a non-essential amino acid (a build block of proteins). It can be produced by the body and is used to improve athletic performance and exercise capacity, building lean muscle mass, and improving physical functioning. It can be used as a supplement and an additive in functional foods.

Possible Side Effects of Beta-Alanine

Although Beta-Alanine generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Ingestion of more than 800 mg of beta-alanine in a single dose has been shown to cause mild burning or flushing of the skin. This may be alleviated by taking doses with meals or by taking a time-release formulation of beta-alanine.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Beta-Alanine is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Beta-Alanine populations. Better consult to your doctor if you would like to intake Beta-Alanine.

 

 

 

Related Research

1. Ingesting a preworkout supplement containing caffeine, creatine, β-alanine, amino acids, and B vitamins for 28 days is both safe and efficacious in recreationally active men. [Nutr Res. 2014 May] Author: Kendall KL, Moon JR, Fairman CM, Spradley BD, Tai CY, Falcone PH, Carson LR, Mosman MM, Joy JM, Kim MP, Serrano ER, Esposito EN.

2. Role of beta-alanine supplementation on muscle carnosine and exercise performance. [Med Sci Sports Exerc. 2010 Jun] Author: Artioli GG, Gualano B, Smith A, Stout J, Lancha AH Jr.

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L-Aspartic Acid Side Effects

L-Aspartic Acid is a white crystal or crystalline powder. It improves biological quality of protein and acts as a nutrient and dietary supplement. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Aspartic Acid?

L-Aspartic Acid, also known as Aspartate, is an amino acid that presents itself as a white odorless powder that is characteristic of an acid-like taste. It is slightly water soluble and insoluble in fat. It is used as a food additive to improve protein content, and can also be used as a flavor enhancer. It has found application as the base of the common sweetener aspartame.

Possible Side Effects of L-Aspartic Acid

Although L-Aspartic Acid generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Asthma
  • Abdominal pain
  • Gout
  • Bloating
  • Diarrhea
  • Allergies

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Aspartic Acid is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Aspartic Acid populations. Better consult to your doctor if you would like to intake L-Aspartic Acid.

 

 

Related Research

1. Effect of l-aspartic acid on the growth, structure and spectral studies of Zinc (tris) Thiourea Sulphate (ZTS) single crystals. [Spectrochim Acta A Mol Biomol Spectrosc. 2014 Nov 11] Author: Samuel BS, Krishnamurthy R, Rajasekaran R.

2. Synthesis and characterization of novel stimuli-responsive hydrogels based on starch and L-aspartic acid. [Carbohydr Polym. 2013 Nov 6] Author: Vakili MR, Rahneshin N.

3. Molecularly imprinted polymer-matrix nanocomposite for enantioselective electrochemical sensing of D- and L-aspartic acid. [Mater Sci Eng C Mater Biol Appl. 2013 Oct] Author: Prasad BB, Srivastava A, Tiwari MP.

4. Amphiphilic poly(L-aspartic acid) copolymer nanoparticles for cyclosporine A delivery. [J Nanosci Nanotechnol. 2013 Feb] Author: Han S, Sun Y, Su S, Hu L, Wu Y.

5. Biodegradable and redox-responsive chitosan/poly(L-aspartic acid) submicron capsules for transmucosal delivery of proteins and peptides. [J Mater Sci Mater Med. 2013 Apr] Author: Zheng C, Zhang XG, Sun L, Zhang ZP, Li CX.

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L-Serine Side Effects

L-Serine is an amino acid, which is produced by fermentation and turned into white crystals. It is commonly used as nutritional enhancer found in nutritional sport drinks. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Serine?

L-Serine is a white crystalline powder. Secondly, L-Serine is also widely applied in food. Few lysine could help to promote cerebrum growth, body strengthening and intelligence improvement. Thirdly, L-Serine could work in feed. This product could enhance organism resistance to disease promote growth, strengthen animals appetite and then increase the output capacity of lean meat. What’s more, L-Serine could be used as the biochemical reagents, food additives, accessorysubstance (eg. skin nutrition additives in cosmetic) and the natural moisturizing agent in some cosmetics and skin care products.

Possible Side Effects of L-Serine

Although L-Serine generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may: Tiredness, Anxiety, Chronic Fatigue, Neurotoxicity, Depression.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Serine is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Serine populations. Better consult to your doctor if you would like to intake L-Serine.

 

 

 

 

Related Research

1. Essentiality of de novo L-serine synthesis for embryonic development and higher functions. [Seikagaku. 2014 Jun] Author: Furuya S, Sayano T, Esaki K.

2. Construction of an L-serine producing Escherichia coli via metabolic engineering. [J Ind Microbiol Biotechnol. 2014 Jul 6.] Author: Gu P, Yang F, Su T, Li F, Li Y, Qi Q.

3. Effect of Cofactor Folate on the Growth of Corynebacterium glutamicum SYPS-062 and L-Serine Accumulation. [Appl Biochem Biotechnol. 2014 May 25] Author: Zhang X, Xu G, Li H, Dou W, Xu Z.

4. L-serine treatment may improve neurorestoration of rats after permanent focal cerebral ischemia potentially through improvement of neurorepair. [PLoS One. 2014 Mar 26] Author: Sun L, Qiang R, Yang Y, Jiang ZL, Wang GH, Zhao GW, Ren TJ, Jiang R, Xu LH.

5. Ruthenium-nitrosyl complexes with glycine, L-alanine, L-valine, L-proline, D-proline, L-serine, L-threonine, and L-tyrosine: synthesis, X-ray diffraction structures, spectroscopic and electrochemical properties, and antiproliferative activity. [Inorg Chem. 2014 Mar 3] Author: Rathgeb A, Böhm A, Novak MS, Gavriluta A, Dömötör O, Tommasino JB, Enyedy EA, Shova S, Meier S, Jakupec MA, Luneau D, Arion VB.

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L-Tryptophan Side Effects

L-Tryptophan is used in supplements and baby food to help sleeping and losing weight. It is commonly used as an additive for functional food products and dietary supplements. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Tryptophan?

L-Tryptophan is an essential amino acid and a main building block of protein. Like other amino acids, L-Tryptophan is one of the building blocks of protein, but unlike some amino acids, L-Tryptophan is considered essential because the body cannot manufacture its own. L-Tryptophan plays many roles in animals and humans alike, but perhaps most importantly, it is an essential precursor to a number of neurotransmitters in the brain. As such, L-Tryptophan is the only substance normally found in the diet that can be converted into serotonin. Since serotonin, in turn, is converted in the brain into melatonin, L-Tryptophan clearly plays a role in balancing mood and sleep patterns.

Possible Side Effects of L-Tryptophan

  • Many side effects can occur with L-tryptophan, some of which are quite dangerous. For example, L-tryptophan can cause serious conditions called eosinophilia-myalgia syndrome or serotonin syndrome. Contact your healthcare provider immediately if you notice symptoms of these conditions, such as nerve pain, difficulty walking, or very severe muscle pain. Other side effects are not as serious and may include headaches, nausea, and diarrhea.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Tryptophan is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Tryptophan populations. Better consult to your doctor if you would like to intake L-Tryptophan.

 

Related Research

1. Calmatives for the excitable horse: a review of L-tryptophan. [Vet J. 2005 Jul] Author: Grimmett A, Sillence MN.

2. Safety of L-tryptophan for pigs. [J Anim Sci. 1991 Jul] Author: Chung TK, Gelberg HB, Dorner JL, Baker DH.

3. Is L-tryptophan safe? [Aust N Z J Psychiatry. 1988 Dec] Author: During MJ, Freese A.

4. Enhancement of the antidepressant response to L-tryptophan by a liver pyrrolase inhibitor: a rational treatment approach. [Neuropsychobiology. 1978] Author: Shopsin B.

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L-Tyrosine Side Effects

L-Tyrosine is an amino acid that the body used to synthesize protein. It is found naturally in high protein foods, such as peanuts, turkey, chicken and soy. It is a white crystalline powder and is used as a nutritional enhancer. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Tyrosine?

L-Tyrosine is a non-essential amino acid that can be synthesized by the body. It can be used to regulate mood and stimulate the nervous system. It’s also used in the treatment of chronic fatigue and to speed up metabolism.

Possible Side Effects of L-Tyrosine

Although L-Tyrosine generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • nausea, heartburn;
  • headache;
  • joint pain; or
  • feeling tired.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Tyrosine is considered safe.

Suggested Dosage

If you do not have any need to, you should not take L-tyrosine as supplements without consulting your doctor. Research has revealed that 100 milligrams per 2.2 pounds of body weight or an average of about 7 grams for average-sized people are safe to use for those that suffer from the aforementioned conditions.

However, a dose of 500 milligrams to 1500 milligrams per day of supplemental tyrosine is mostly recommended for those taking it for stress management, weight loss and body building. Generally, the L-Tyrosine dosage would depend on why you are taking the drug. Always ask your caregiver about how much tyrosine supplements to take in.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Tyrosine populations. Better consult to your doctor if you would like to intake L-Tyrosine.

 

Related Research

1. Review of L-tyrosine confirming its safe human use as an adjuvant. [J Appl Toxicol. 2002 Sep-Oct] Author: Baldrick P, Richardson D, Wheeler AW.

2. Administration of supplemental L-tyrosine with phenelzine: a clinical literature review. [Clin Pharmacol. 2014 Jul 22] Author: Hinz M, Stein A, Cole T, Ryan P.

3. Novel synthesis of gold nanoclusters templated with l-tyrosine for selective analyzing tyrosinase. [Anal Chim Acta. 2014 Aug 20] Author: Yang X, Luo Y, Zhuo Y, Feng Y, Zhu S.

4. Evaluation of Various Factors Affecting Bioconversion of l-Tyrosine to l-DOPA by Yeast Yarrowia lipolytica-NCIM 3450 Using Response Surface Methodology. [Nat Prod Bioprospect. 2014] Author: Gurme ST, Surwase SN, Patil SA, Jadhav JP.

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L-Lysine Monohydrochloride Side Effects

L-Lysine Monohydrochloride is one of the important compositions of protein. It used as an enhancing agent to rice and flour, and it may also be an efficient dietary supplement providing health benefits like improving growth, adjusting appetite, reducing diseases, and making the body stronger. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Lysine Monohydrochloride?

L-Lysine Monohydrochloride is a branched-chain amino acid. The human body cannot synthesize L-Leucine therefore, it must be ingested. It helps preserve lean muscle tissue, it supplies the body with energy when under stress, it preserves muscle glycogen, it maintains nitrogen balance, and it enhances thinking abilities that can decline as physical activity becomes more intense. It also works to heal bone, skin and muscle tissue and is commonly used as a treatment for cold sores.

Possible Side Effects of L-Lysine Monohydrochloride

Although L-Lysine Monohydrochloride generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • 1. Allergic Reactions

    An excessive intake of lysine causes allergic reactions. Although the allergies differ from person to person, patients will often experience swellings around the face, lips and tongue. It also causes blocking of the throat, and difficulties in breathing.

    2. Interaction with Antibiotics

    Lysine is not to be mixed with other drugs unless recommended by a doctor. Antibiotics such as gentamicin, tobracin, netilmicin, neomycin, amikacin, kanamycin, streptomycin and tobramycin react with lysine causing adverse effects. These can cause body toxins and can be lethal. It is important to take the supplements under strict medical guidance.

    3. Causing Health Disorders

    The over consumption of lysine prevents proper blood circulation, and it hardens the arteries. This can cause serious medical conditions like heart attack, cardiovascular complications and stroke. Lysine is responsible for hardening of arteries; it also causes stomach cramps, diarrhea and gall stones. Anyone with any medical conditions needs to seek medical advice before using lysine. It is forbidden for people with heart, kidney, and liver conditions. Expectant women and nursing mothers are also cautioned against taking lysine since its negative effects are unclear.

    4. Heavy Metals

    These amino acids have been found to contain heavy metals, which are harmful to your health. These can cause death as a result of poisoning. Since there is no regulatory standard against the manufacture of lysine, caution should be taken when using it. In case of an overdose, immediate medical treatment should be sought.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Lysine Monohydrochloride is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Lysine Monohydrochloride populations. Better consult to your doctor if you would like to intake L-Lysine Monohydrochloride.

 

 

 

Related Research

1. Studies on the effect of polymer coating on solution grown hygroscopic non-linear optical single crystal of L-lysine monohydrochloride. [Spectrochim Acta A Mol Biomol Spectrosc. 2012 Nov] Author: Rani N, Vijayan N, Maurya KK, Haranath D, Saini P, Rathi B, Wahab MA, Bhagavanarayana G.

2. Effects of L-lysine monohydrochloride on insulin and blood glucose levels in spinal cord injured rats. [Chin Med J (Engl). 2010 Mar 20] Author: Zhang TL, Zhao YW, Liu XY, Ding SJ.

3. Probes on L-lysine monohydrochloride dihydrate: a semiorganic nonlinear optical crystal. [Spectrochim Acta A Mol Biomol Spectrosc. 2008 Nov 15] Author: Krishnakumar V, Nagalakshmi R, Manohar S, Kocsis L.

4. Plasticity and slip system of plate-shaped crystals of L-lysine monohydrochloride dihydrate. [Pharm Res. 2002 Apr] Author: Bandyopadhya R, Grant DJ.

5. Influence of crystal shape on the tableting performance of L-lysine monohydrochloride dihydrate. [J Pharm Sci. 2001 May] Author: Sun C, Grant DJ.

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L-Lysine Side Effects

L-Lysine is an essential amino acid in the body, aiding in the synthesis of protein. It is most commonly used in beverages, rice, flower and canned goods as a nutritional supplement. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Lysine?

L-Lysine is an amino acid that presents itself as a white crystalline powder that is soluble in water, and almost insoluble in alcohol and ether. With no odor and a bitter taste, it is used as a food preservative and has found application in boiled rice and noodles; custard cream; cooked vegetables and soups; potato salad; sliced fish and sushi; and steamed cakes.

Possible Side Effects of L-Lysine

Although L-Lysine generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • stomach pain and diarrhea.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Lysine is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Lysine populations. Better consult to your doctor if you would like to intake L-Lysine.

 

 

 

Related Research

1. In vivo toxicity and biodistribution of intraperitoneal and intravenous poly-L-lysine and poly-L-lysine/poly-L-glutamate in rats. [J Mater Sci Mater Med. 2014 May] Author: Isaksson K, Akerberg D, Posaric-Bauden M, Andersson R, Tingstedt B.

2. Enhanced epsilon-poly-L-lysine production from Streptomyces ahygroscopicus by a combination of cell immobilization and in situ adsorption. [J Microbiol Biotechnol. 2012 Sep] Author: Liu S, Wu Q, Zhang J, Mo S, Yang X, Xiao C

3. In vivo distribution of avidin-conjugated MX35 and (211)At-labeled, biotinylated poly-L-lysine for pretargeted intraperitoneal α-radioimmunotherapy. [Cancer Biother Radiopharm. 2011 Dec] Author: Frost SH, Bäck T, Chouin N, Jensen H, Hultborn R, Jacobsson L, Lindegren S.

4. Study on galactose-poly(ethylene glycol)-poly(L-lysine) as novel gene vector for targeting hepatocytes in vitro. [J Biomater Sci Polym Ed. 2012] Author: Hu HM, Zhang X, Zhong NQ, Pan SR.

5. Isolation and characterization of a novel ε-poly-L-lysine producing strain: Streptomyces griseofuscus. [J Ind Microbiol Biotechnol. 2011 Apr] Author: Li S, Tang L, Chen X, Liao L, Li F, Mao Z.

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L-Arginine Side Effects

L-Arginine is an amino acid used as supplement form and obtained naturally in the diet. It appears as a white crystalline powder, and is necessary for the production of protein. It can also help rid the body of ammonia (a waste product) and stimulate the release of insulin. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Arginine?

L-Arginine is one of the most common 20 naturally occurring amino acids. It is synthesized from citrulline by cytosolic enzymes and argininosuccinate lyase. It plays an imperative role in immune function, cell division, the healing of wounds and the release of hormones. L-Arginine has a loss on drying of not more than .5% with a heavy metal density of no more than .0015%. L-Arginine is found in a wide variety of plant and animal products, including meat, seafood, dairy products, wheat germ, nuts and soybeans, and is known to have cardiovascular benefits. L-Arginine is alkaline and has a bitter taste. It also helps neutralize acid nutrients such as ascorbic acid, niacin, pyroglutamic acid, and OKG.

Possible Side Effects of L-Arginine

Although L-Arginine generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

-abdominal pain
-bloating
-diarrhea

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Arginine is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Arginine populations. Better consult to your doctor if you would like to intake L-Arginine.

 

 

 

Related Research

1. The pharmacodynamics of L-arginine. [Altern Ther Health Med. 2014 May-Jun] Author: Böger RH.

2. A randomized pilot study of L-arginine infusion in severe falciparum malaria: preliminary safety, efficacy and pharmacokinetics. [PLoS One. 2013 Jul 29] Author: Yeo TW, Lampah DA, Rooslamiati I, Gitawati R, Tjitra E, Kenangalem E, Price RN, Duffull SB, Anstey NM.

3. A randomized controlled trial of inhaled L-arginine in patients with cystic fibrosis. [J Cyst Fibros. 2013 Sep] Author: Grasemann H, Tullis E, Ratjen F.

4. The effect of L-arginine on arterial stiffness and oxidative stress in chronic kidney disease. [Indian J Nephrol. 2012 Sep] Author: Annavarajula SK, Dakshinamurty KV, Naidu MU, Reddy CP.

5. Does L-arginine supplementation play a role in cerebral small vessels disease? Implication in the treatment of leukoaraiosis. [Med Hypotheses. 2011 Oct] Author: Calabrò RS, Gervasi G, Bramanti P.

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L-Cysteine Side Effects

L-Cysteine E920 is an essential amino acid protein supplement used in nutraceutical, nutritional supplement, and food additive applications. Though L-Cysteine E920 is considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Cysteine E920?

L-Cysteine E920 is an amino acid that is used in food processing. This product appears as white crystals or crystalline powder with a strong acidic taste. L-Cysteine is used for bread fermentation and is used to prevent ageing in the food industry.

Possible Side Effects of L-Cysteine E920

Although L-Cysteine E920 generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • upset stomach, nausea, vomiting, diarrhea, persistent stomach cramps, body aches, headache, and general gastrointestinal discomfort.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Cysteine is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Cysteine populations. Better consult to your doctor if you would like to intake L-Cysteine.

 

 

 

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L-Glutamic Acid Side Effects

Glutamic acid E620 is often used as a food additive and flavor enhancer in the form of its salt, known as monosodium glutamate (MSG). Though Glutamic acid E620 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Glutamic acid E620?

L-Glutamic Acid E620 is a protein-bound non-essential amino acid that is commonly found in plants and animals. It is naturally found in foods such as cheese, meat, mushrooms, and soybeans. As a food additive, L-Glutamic Acid is widely used as a flavor enhancer in items with a meaty or savory taste.

Possible Side Effects of Glutamic acid E620

Although Glutamic acid E620 generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Blood in urine
  • changes in skin color
  • chills
  • cold hands and feet
  • confusion
  • cough
  • difficulty swallowing
  • dizziness
  • fainting
  • fast heartbeat
  • fever
  • frequent and painful urination
  • headache
  • hives
  • itching
  • lightheadedness
  • lower back or side pain
  • pain, redness, or swelling in arm or leg
  • puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
  • rapid, shallow breathing
  • shortness of breath
  • skin rash
  • stomach pain
  • sudden decrease in amount of urine
  • tightness in chest
  • unusual tiredness or weakness
  • wheezing

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Glutamic acid E620 is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Glutamic acid populations. Better consult to your doctor if you would like to intake Glutamic acid E620.

 

 

 

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L-Methionine Side Effects

L-Methionine is an essential amino acid. It is beneficial in treating liver disease and benefits skin tone and elasticity, nails and hair. It is also important for proper cardiovascular and muscular functions and is used in the treatment of chronic depression. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Methionine?

L-Methionine is a white crystalline powder and an essential amino acid found in high protein foods such as meat, fish, and dairy. This amino acid is used to help the body break down fat, build muscle, and aid in the removal of heavy metals from the body to ensure proper functioning of the liver, kidneys, and bladder. L-Methionine is used as a nutritional food additive and is of particular interest to vegetarians and vegans who may not ingest enough protein in their normal diet.

Possible Side Effects of L-Methionine

Although L-Methionine generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Drowsiness
  • nausea and vomiting

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Methionine is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Glucono Delta Lactone populations. Better consult to your doctor if you would like to intake L-Methionine.

 

 

 

Related Research

1. 2-keto-4-(methylthio)butyric acid (keto analog of methionine) is a safe and efficacious precursor of L-methionine in chicks. [J Nutr. 2007 Aug] Author: Dilger RN, Kobler C, Weckbecker C, Hoehler D, Baker DH.

2. The keto acid of methionine is a safe and efficacious substitute for dietary L-methionine: the answer from chick bioassays. [J Nutr. 2007 Aug] Author: Stipanuk MH.

3. Treatment of AIDS-associated myelopathy with L-methionine: a placebo-controlled study. [Neurology. 2004 Oct 12] Author: Di Rocco A, Werner P, Bottiglieri T, Godbold J, Liu M, Tagliati M, Scarano A, Simpson D.

4. Does L-Methionine Have Health Benefits? A Scientist Explains

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L-Alanine Side Effects

L-Alanine is made up of white crystals or a crystalline powder, and is used as an additive to improve the nutritional value in food and drinks such as bread, tea, and dairy products. L-Alanine is an amino acid that improves the body’s utilization of protein.  Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Alanine?

L-Alanine is a non-essential amino acid produced by the human body that is involved in the metabolism of sugar and acids. As a dietary supplement, it can help reduce body fat levels, promote insulin regulation, and support prostate health. It is mainly used in nutritional supplements and as a sweetener in products that have undergone non-enzymatic browning such as bread products, meats, malted barley, roasted coffee, and maple syrup.

Possible Side Effects of L-Alanine

Although L-Alanine generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • paraesthesia, or tingling sensations.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Alanine is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Alanine populations. Better consult to your doctor if you would like to intake L-Alanine.

 

 

 

Related Research

1. Characterization of a meso-chiral isomer of a hexanuclear Cu(ii) cage from racemization of the l-alanine Schiff base. [Dalton Trans. 2014 Jul 15] Author: Rajesh CM, Ray M.

2. Structural Analysis and Mutant Growth Properties Reveal Distinctive Enzymatic and Cellular Roles for the Three Major L-Alanine Transaminases of Escherichia coli. [PLoS One. 2014 Jul 11] Author: Peña-Soler E, Fernandez FJ, López-Estepa M, Garces F, Richardson AJ, Quintana JF, Rudd KE, Coll M, Vega MC.

3. Prolonged continuous intravenous infusion of the dipeptide L-alanine- L-glutamine significantly increases plasma glutamine and alanine without elevating brain glutamate in patients with severe traumatic brain injury. [Crit Care. 2014 Jul 2] Author: Nägeli M, Fasshauer M, Sommerfeld J, Fendel A, Brandi G, Stover JF.

4. Thiophenyl-substituted triazolyl-thione L-alanine: asymmetric synthesis, aggregation and biological properties. [Amino Acids. 2014 Jun 22] Author: Saghyan AS, Simonyan HM, Petrosyan SG, Geolchanyan AV, Roviello GN, Musumeci D, Roviello V.

5. Cycling Time Trial Performance May Be Impaired by Whey Protein and L-Alanine Intake During Prolonged Exercise. [Int J Sport Nutr Exerc Metab. 2014 Jun 17] Author: Schroer AB, Saunders MJ, Baur DA, Womack CJ, Luden ND.

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D-Ribose Side Effects

Ribose is a carbohydrate with the formula C5H10O5; specifically, it is a pentosemonosaccharide (simple sugar) with linear form H−(C=O)−(CHOH)4−H, which has all the hydroxyl groups on the same side in the Fischer projection. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is D-Ribose?

D-Ribose is a white or slightly yellow crystalline powder. It is a pentose monosaccharide or simply known as a simple sugar. This product is known to generate and recover ATP levels and can be used to promote a healthy heart and help the body muscles recover more quickly after exercise. It can be found in health foods and other supplements.

Possible Side Effects of D-Ribose

Although D-Ribose generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • D-Ribose can cause stomach discomfort such as diarrhea, stomach pain and nausea.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. D-Ribose is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to D-Ribose populations. Better consult to your doctor if you would like to intake D-Ribose.

 

 

Related Research

1. Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects. [J Clin Pharmacol. 2013 Nov 23] Author: Thompson J, Neutel J, Homer K, Tempero K, Shah A, Khankari R.

2. Evaluation of α-D-ribofuranose (D-ribose) toxicity after intravenous administration to rabbits. [Hum Exp Toxicol. 2012 Aug] Author: Ismail ZB, Abu-Baker N, Alzoubi K, Al-Zhgoul M, Al-Essa MK, Khlouf S, Al-Saleh A, Al-Omari B, Abu-Tayeh R, Shomaf M, Battah A, Al-Hadidi K.

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