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Sodium Citrate Side Effects

Sodium Citrate E331(i) is used to enhance flavor and maintain stability of active ingredients in dairy products and carbonated drinks. Though Sodium Citrate E331(i) is considered safe, some are convinced it has potentially dangerous health effects.

What Is Sodium Citrate E331(i)?

Sodium Citrate E331(i) is a white granular crystal or a crystalline powder that is odorless with a slightly acidic taste. Sodium Citrate is used in the food and beverage industry as a flavoring agent, acidity regulator, and stabilizer. Sodium Citrate E331(i) is used in ice cream, to prevent fat globules from sticking together. Sodium Citrate E331(i) is also used to regulate the pH level of soft drinks, and as an emulsifier for oils when making cheese.

Possible Side Effects of Sodium Citrate E331(i)

Though Sodium Citrate E331(i) is regarded as safe supplement, there maybe some side effects:

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • swelling, tingling, or numbness in your hands or feet;
  • muscle twitching or pain, leg pain or cramps;
  • unusual weakness, rapid and shallow breathing, fast or slow heart rate, dizziness, confusion, or mood changes;
  • feeling restless, nervous, or irritable;
  • black, bloody, or tarry stools;
  • severe or ongoing diarrhea; or
  • seizure (convulsions).

Less serious side effects of citric acid / sodium citrate E331(i) may include:

  • nausea, or vomiting, stomach pain;
  • mild or occasional diarrhea; or
  • mild stomach pain.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium Citrate E331(i) is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sodium Citrate populations. Better consult to your doctor if you would like to intake Sodium Citrate E331(i).

 

 

 

Related Research

1. Loss of antimicrobial effect of trisodium citrate due to ‘lock’ spillage from haemodialysis catheters. [Nephrol Dial Transplant. 2014 Apr] Author: Schilcher G, Schneditz D, Ribitsch W, Horina JH, Hoenigl M, Valentin T, Rosenkranz AR, Krause R.

2. Facile synthesis of alumina hollow microspheres via trisodium citrate-mediated hydrothermal process and their adsorption performances for p-nitrophenol from aqueous solutions. [J Colloid Interface Sci. 2013 Mar 15] Author: Zhou J, Wang L, Zhang Z, Yu J.

3. Incompatibility of contrast medium and trisodium citrate. [Cardiovasc Intervent Radiol. 2013 Feb] Author: Delcour C, Bruninx G.

4. Evaluation of interparticle interaction between colloidal Ag nanoparticles coated with trisodium citrate and safranine by using FRET: spectroscopic and mechanistic approach. [J Photochem Photobiol B. 2012 Aug 1] Author: Mokashi VV, Gore AH, Sudarsan V, Rath MC, Han SH, Patil SR, Kolekar GB.

5. Trisodium citrate induced protein precipitation in haemodialysis catheters might cause pulmonary embolism. [Nephrol Dial Transplant. 2012 Jul] Author: Schilcher G, Scharnagl H, Horina JH, Ribitsch W, Rosenkranz AR, Stojakovic T, Polaschegg HD.

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Vanillin Side Effects

Vanillin can be used in food and beverage applications as a flavoring agent. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Vanillin?

Vanillin is a phenolic aldehyde, an organic compound with the molecular formula C8H8O3. Vanillin is widely used in making foods, drinks, tobacco, wines, medicines, chemicals and various cosmetics. The largest use of vanillin is as a flavoring, usually in sweet foods. The ice cream and chocolate industries together comprise 75% of the market for vanillin as a flavoring, with smaller amounts being used in confections and baked goods.

Possible Side Effects of Vanillin

Though Vanillin is regarded as safe supplement, there maybe some side effects:

Possible short-term side effects

  • mild headaches
  • allergic reaction for those who are sensitive

Possible long-term side effects

  • may kill brain cells
  • could be considered an addictive substance

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Vanillin is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Vanillin populations. Better consult to your doctor if you would like to intake Vanillin.

 

 

Related Research

1. Vanillin Analog – Vanillyl Mandelic Acid, a Novel Specific Inhibitor of Snake Venom 5′-Nucleotidase. [Arch Pharm (Weinheim). 2014 Jul 15] Author: Arun R, Arafat AS, D’Souza CJ, Sivaramakrishnan V, Dhananjaya BL.

2. Comprehensive proteome analysis of the response of Pseudomonas putida KT2440 to the flavor compound vanillin. [J Proteomics. 2014 Jul 12] Author: Simon O, Klaiber I, Huber A, Pfannstiel J.

3. Inhibitory effect of vanillin on cellulase activity in hydrolysis of cellulosic biomass. [Bioresour Technol. 2014 Sep] Author: Li Y, Qi B, Wan Y.

4. Improvement of membrane performances to enhance the yield of vanillin in a pervaporation reactor. [Membranes (Basel). 2014 Feb 28] Author: Camera-Roda G, Cardillo A, Loddo V, Palmisano L, Parrino F.

5. Research on a novel poly (vinyl alcohol)/lysine/vanillin wound dressing: Biocompatibility, bioactivity and antimicrobial activity. [Burns. 2014 Jun 18] Author: Zhou G, A R, Ge H, Wang L, Liu M, Wang B, Su H, Yan M, Xi Y, Fan Y.

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Agar Agar Side Effects

Agar Agar E406 is a milky or yellowish fine powder used as an ingredient in desserts throughout Asia. It is mainly used to make jellies, puddings and custards. Though Agar Agar E406 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Agar Agar E406?

Agar Agar E406 is a natural hydrocolloid extracted from several species of red algae. It is used for thickening and gelling foods without affecting color or flavor. Since its gelling power is ten times higher than animal gelatine, it is effective at very low levels. In addition, Agar-Agar has a very high content of soluble fiber (almost 90% by weight) and minerals, so it is often included in dietetic foods. Unlike other food hydrocolloids such as carrageenan and pectin, agar does not require other agents (such as salts) to form gels. Thus, it contributes much less to ash content than other gelling agents. Agar-Agar can be used in confectionery (jellies, caramels, toppings, jams, cake and doughnut icings), dairy products, canned foods, baked goods, soups and casseroles.

Possible Side Effects of Agar Agar E406

Though Agar Agar E406 is regarded as safe supplement, there maybe some side effects:

  1. Loss of appetite
  2. Weak digestion
  3. Loose stools

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Agar Agar E406 is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Agar Agar E406 populations. Better consult to your doctor if you would like to intake Agar Agar.

 

 

Related Research

1. Immobilization of pectin degrading enzyme from Bacillus licheniformis KIBGE IB-21 using agar-agar as a support. [Carbohydr Polym. 2014 Feb 15] Author: Rehman HU, Aman A, Zohra RR, Qader SA.

2. Conventional and microwave pyrolysis of a macroalgae waste from the Agar-Agar industry. Prospects for bio-fuel production. [Bioresour Technol. 2014 Jan] Author: Ferrera-Lorenzo N, Fuente E, Bermúdez JM, Suárez-Ruiz I, Ruiz B.

3. Antimicrobial activity of highly stable silver nanoparticles embedded in agar-agar matrix as a thin film. [Carbohydr Res. 2010 Oct 13] Author: Ghosh S, Kaushik R, Nagalakshmi K, Hoti SL, Menezes GA, Harish BN, Vasan HN.

4. Use of a new gelling agent (Eladium©) as an alternative to agar-agar and its adaptation to screen biofilm-forming yeasts. [Appl Microbiol Biotechnol. 2010 Nov] Author: Gognies S, Belarbi A.

5. [Gel-producing properties of exopolysaccharide acrylamide in composition with agar-agar]. [Mikrobiol Z. 2004 Nov-Dec] Author: Vashchenko LN, Litvinchuk OA, Gvozdiak RI, Votselko SK.

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Xanthan Gum Side Effects

Xanthan Gum E415 is a food thickening agent in salad dressings. It appears as a dry fine powder, and is added to a liquid medium to form a gum. It can be used in gluten-free baking and to thicken egg-substitutes. Though Xanthan Gum E415 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Xanthan Gum E415?

Xanthan Gum E415 is an odorless, cream colored powder produced by fermentation of Xanthomonas Campestris. It is a complex long chained polysaccharide with a high content of trisaccharide side chains that readily dissolve in cold and hot water. The solutions are very viscous, highly pseudoplastic, and very resistant to pH-variations, enzymatic degradation, and temperature variations. Xanthan Gum has excellent freeze/thaw stability and is compatible with all commercial thickeners and alcohol. It is used as a thickener, stabilizer, emulgator, or foam stabilizer in food and beverages. The application of Xanthan Gum E415 such as in fruit juices, ice creams, soy sauce, oyster sauce, baked goods, gels, soft drinks, salad dressings, instant noodles, sausages, canned meats, cheese, cakes, bread, dehydration foods, and canned pet food.

Possible Side Effects of Xanthan Gum E415

Though Xanthan Gum E415 is regarded as safe supplement, there maybe some side effects:

  • Bloating and Intestinal Gas from consuming large quantities
  • Nose and Throat Irritation if exposed to the powder for sustained periods
  • Lung Problems
  • Nausea
  • Vomiting
  • Difficulty Passing Stool
  • Headache
  • Stomach or Abdominal Pain

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Xanthan Gum is considered safe.

Suggested Dosage

10 milligrams per kilogram per day as a food additive, 15 grams per day as a laxative and 12 grams per day as a muffin ingredient for diabetics

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Xanthan Gum populations. Better consult to your doctor if you would like to intake Xanthan Gum E415.

 

 

Related Research

1. The effects of a xanthan gum-based thickener on the swallowing function of patients with dysphagia [Aliment Pharmacol Ther. 2014 May] Author: By Rofes L, Arreola V, Mukherjee R, Swanson J, Clavé P

2. Rheological characterization of an acetaminophen jelly. [Indian J Pharm Sci. 2013 Jul] Author: Inoue Y, Takahashi R, Okada H, Iwasaki Y, Murata I, Kanamoto I.

3. Effect of cell immobilization on heat-induced sublethal injury of Escherichia coli, Salmonella Typhimurium and Listeria innocua. [Food Microbiol. 2013 Dec] Author: Noriega E, Velliou E, Van Derlinden E, Mertens L, Van Impe JF.

4. Efficacy and safety of chondroitin sulfate/xanthan gum versus polyethylene glycol/propylene glycol/hydroxypropyl guar in patients with dry eye. [Clin Ophthalmol. 2013] Author: Llamas-Moreno JF, Baiza-Durán LM, Saucedo-Rodríguez LR, Alaníz-De la O JF.

5. Processing of waxy starch/xanthan gum mixtures within the gelatinization temperature range. [Carbohydr Polym. 2013 Jul 25] Author: Heyman B, Depypere F, Van der Meeren P, Dewettinck K.

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Propylene Glycol Alginate Side Effects

Propylene glycol alginate (PGA) E405 is an additive used mainly as a thickening agent in certain types of food. Though Propylene Glycol Alginate E405 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Propylene Glycol Alginate E405?

Propylene Glycol Alginate E405 is an ester of alginic acid originally derived from brown algae. This product appears as a white or slightly yellowish color and in powder form. It is used as a thickening and emulsifying agent, is acid resistant, and is soluble in water and acid. Propylene Glycol Alginate E405 is used in dairy products, salad dressing, fruit, lactic acid beverages, beer, and instant food.

Possible Side Effects of Propylene Glycol Alginate E405

Though Propylene Glycol Alginate E405 is regarded as safe supplement, there maybe some side effects: It can cause stomach upset and nausea, whether it’s ingested or used on the skin as a cosmetic. When it is only used in cosmetic, it can cause allergic reactions that include hair loss, rashes, and eye irritations. Cosmetic use is the most common cause of side effects. Other skin-related allergies can occur when household cleaners that contains this ingredient are used.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Propylene Glycol Alginate E405 is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Propylene Glycol Alginate E405 populations. Better consult to your doctor if you would like to intake Propylene Glycol Alginate E405.

Related Research

1. Effects of propylene glycol alginate and sucrose esters on the physicochemical properties of modified starch-stabilized beverage emulsions. [Molecules. 2014 Jun 24] Author: Cheong KW, Mirhosseini H, Hamid NS, Osman A, Basri M, Tan CP.

2. Determination of M/G ratio of propylene glycol alginate sodium sulfate by HPLC with pre-column derivatization. [Carbohydr Polym. 2014 Apr 15] Author: Wu J, Zhao X, Ren L, Xue Y, Li C, Yu G, Guan H.

3. Enamel matrix derivative in propylene glycol alginate for treatment of infrabony defects with or without systemic doxycycline: 12- and 24-month results. [J Periodontol. 2014 May] Author: Eickholz P, Röllke L, Schacher B, Wohlfeil M, Dannewitz B, Kaltschmitt J, Krieger JK, Krigar DM, Reitmeir P, Kim TS.

4. Interfacial and foaming interactions between casein glycomacropeptide (CMP) and propylene glycol alginate. [Colloids Surf B Biointerfaces. 2012 Jun 15] Author: Martinez MJ, Pizones Ruiz-Henestrosa VM, Carrera Sánchez C, Rodríguez Patino JM, Pilosof AM.

5. Integrative design of a poly(ethylene glycol)-poly(propylene glycol)-alginate hydrogel to control three dimensional biomineralization. [Biomaterials. 2011 Apr] Author: Cha C, Kim ES, Kim IW, Kong H.

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Monosodium Glutamate Side Effects

Monosodium glutamate E621, or MSG, is the salt form of the amino acid glutamate. MSG is added to many foods to enhance flavor. Though Monosodium glutamate E621 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Monosodium glutamate E621?

Monosodium Glutamate E621 is a white crystalline granular or powder. It is used to intensify flavors of food and is produced by a bacterial fermentation process with starch or molasses. MSG is not a direct taste enhancer but a complex flavor enhancer for gravies, meats, poultry, sauces, and in other combinations. It is also used to enhance the taste of tobacco.

Possible Side Effects of Monosodium glutamate E621

Though Monosodium glutamate E621 is regarded as safe supplement, there maybe some side effects:

  • Rashes, itching, burning, numbness;
  • Migraines, headaches;
  • Asthma;
  • Irritable bowel syndrome symptoms;
  • Chest tightness, heart palpitations, heart arrhythmia, anxiety;
  • Irritability, restlessness, sleep disturbance; and
  • Obesity

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Monosodium glutamate E621 is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Monosodium glutamate populations. Better consult to your doctor if you would like to intake Monosodium glutamate.

 

 

Related Research

1. The safety evaluation of monosodium glutamate. [J Nutr. 2000 Apr] Author: Walker R, Lupien JR.

2. [The effect of probiotic therapy on development of experimental obesity in rats caused by monosodium glutamate]. [Fiziol Zh. 2014] Author: Savcheniuk OA, Virchenko OV, Falalieieva TM, Beregova TV, Babenko LP, Lazarenko LM, Spivak MIa.

3. Pathological Changes in Hepatocytes of Mice with Obesity-induced Type 2 Diabetes by Monosodium Glutamate. [Yakugaku Zasshi. 2014] Author: Nakadate K, Motojima K, Kamata S, Yoshida T, Hikita M, Wakamatsu H.

4. Biochemical Alterations during the Obese-Aging Process in Female and Male Monosodium Glutamate (MSG)-Treated Mice. [Int J Mol Sci. 2014 Jun 27] Author: Hernández-Bautista RJ, Alarcón-Aguilar FJ, Del C Escobar-Villanueva M, Almanza-Pérez JC, Merino-Aguilar H, Fainstein MK, López-Diazguerrero NE.

5. The sensitivity of male rat reproductive organs to monosodium glutamate. [Acta Med Acad. 2014] Author: Iamsaard S, Sukhorum W, Samrid R, Yimdee J, Kanla P, Chaisiwamongkol K, Hipkaeo W, Fongmoon D, Kondo H.

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Maltodextrin Side Effects

Maltodextrin is used as a thickening or filling agent in frozen food, dairy products, confectionery, soft drinks, fast food, and canned food. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Maltodextrin?

Maltodextrin is a hydrolysis product between starch and starch sugar. It appears as a white or yellow powder, and has good fluidity and solubility, moderate viscosity, emulsification, stability, anti-recrystallization, and low water absorbency. Maltodextrin is used for food and beverage foam with good retention.

Possible Side Effects of Maltodextrin

Though Maltodextrin is regarded as safe supplement, there maybe some side effects: can affect your blood sugar

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Maltodextrin is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Maltodextrin populations. Better consult to your doctor if you would like to intake Maltodextrin.

 

 

Related Research

1. Assessment of the safety of hydrogenated resistant maltodextrin: reverse mutation assay, acute and 90-day subchronic repeated oral toxicity in rats, and acute no-effect level for diarrhea in humans. [J Toxicol Sci. 2013] Author: Yoshikawa Y, Kishimoto Y, Tagami H, Kanahori S.

2. Glycine, glycyl-glycine and maltodextrin based oral rehydration solution. Assessment of efficacy and safety in comparison to standard ORS. [Acta Paediatr Scand. 1990 May] Author: Bhan MK, Sazawal S, Bhatnagar S, Bhandari N, Guha DK, Aggarwal SK.

3. The dietary polysaccharide maltodextrin promotes salmonella survival and mucosal colonization in mice. [PLoS One. 2014 Jul 7] Author: Nickerson KP, Homer CR, Kessler SP, Dixon LJ, Kabi A, Gordon IO, Johnson EE, de la Motte CA, McDonald C.

4. Maltodextrin based proniosomes of nateglinide: Bioavailability assessment. [Int J Biol Macromol. 2014 Aug] Author: Sahoo RK, Biswas N, Guha A, Kuotsu K.

5. Biocatalytic Synthesis of Maltodextrin-Based Acrylates from Starch and α-Cyclodextrin. [Macromol Biosci. 2014 May 26] Author: Kloosterman WM, Spoelstra-van Dijk G, Loos K.

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Gelatin Side Effects

Gelatin is mainly used as a gelling agent in candies, marshmallows, gelatin desserts, ice cream, dips and yogurt. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Gelatin?

Gelatin is a protein made from animal products. Gelatin is a very commonly used food additive that functions as a stabilizer, thickener, or a texturizer. It is used extensively in desserts or sweet confectionery items such as trifles, marshmallows, gummy candies, and, of course, gelatin desserts. Gelatin also works as a thickener in common kitchen items like jams, yogurt, cream cheese and margarine.

Possible Side Effects of Gelatin

Though Gelatin is regarded as safe supplement, there maybe some side effects: Gelatin can cause an unpleasant taste, sensation of heaviness in the stomach, bloating, heartburn, and belching. Gelatin can cause allergic reactions in some people.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Gelatin is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Gelatin populations. Better consult to your doctor if you would like to intake Gelatin.

Related Research

1. Efficacy, safety, and biodegradation of a degradable scleral buckle of chitosan-gelatin polymer in rabbits. [Retina. 2013 May] Author: Xu T, Yang Y, Yu Y, Zhu R, Chen H.

2. Safety biocompatibility of gelatin hemostatic matrix (Floseal and Surgiflo) in neurosurgical procedures. [Surg Technol Int. 2012 Dec] Author: Gazzeri R, Galarza M, Alfier A.

3. Safety of gelatin for volume resuscitation–a systematic review and meta-analysis. [Intensive Care Med. 2012 Jul] Author: Thomas-Rueddel DO, Vlasakov V, Reinhart K, Jaeschke R, Rueddel H, Hutagalung R, Stacke A, Hartog CS.

4. [Effectiveness and safety of using 6% hydroxyethyl starch 130/04 and 4% modified liquid gelatin in neurosurgical patients with massive intraoperative blood loss]. [Anesteziol Reanimatol. 2009 Sep-Oct] Author: Israelian LA, Lubnin AIu.

5. Safety and efficacy of a surgeon-prepared gelatin hemostatic agent compared with FloSeal for hemostasis in laparoscopic partial nephrectomy. [J Endourol. 2009 Feb] Author: Guzzo TJ, Pollock RA, Forney A, Aggarwal P, Matlaga BR, Allaf ME

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Sodium Acetate Anhydrous Side Effects

Sodium Acetate Anhydrous appears as an odorless white powder, and is used as a flavoring agent imparting a salty or vinegary flavor to potato chips. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Sodium Acetate Anhydrous?

Sodium Acetate Anhydrous is the sodium salt of acetic acid. Sodium Acetate Anhydrous is a colorless transparent crystal or white powder. Sodium Acetate Anhydrous is used in the food industry as a seasoning agent. A frequent use of Sodium Acetate Anhydrous is to impart a salt and vinegar flavor to potato chips.

Possible Side Effects of Sodium Acetate Anhydrous

Though Sodium Acetate Anhydrous is regarded as safe supplement, there maybe some side effects:

  • sodium overload
  • excessive hydration
  • dilution of other serum electrolyte concentrations
  • fluid in the lungs, or
  • low levels of blood potassium

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium Acetate Anhydrous is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sodium Acetate Anhydrous populations. Better consult to your doctor if you would like to intake Sodium Acetate Anhydrous.

 

 

Related Research

1. Bacteria contributing to behaviour of radiocarbon in sodium acetate. [Radiat Prot Dosimetry. 2011 Jul] Author: Ishii N, Uchida S.

2. Effect of reduced oxygen atmosphere and sodium acetate treatment on the microbial quality changes of seer fish (Scomberomorus commerson) steaks stored in ice. [Food Microbiol. 2010 Jun] Author: Mohan CO, Ravishankar CN, Srinivasa Gopal TK, Lalitha KV, Asok Kumar K.

3. Effects of a new maintenance fluid containing sodium acetate as the base component and electrolytes during renal biopsies in patients with chronic glomerulonephritis. [Arzneimittelforschung. 2004] Author: Tomino Y, Funabiki K, Suzuki S, Maeda K, Sekizuka K, Fukui M, Horikoshi S.

4. Effects of infused sodium acetate, sodium lactate, and sodium beta-hydroxybutyrate on energy expenditure and substrate oxidation rates in lean humans. [Am J Clin Nutr. 1993 Nov] Author: Chioléro R, Mavrocordatos P, Burnier P, Cayeux MC, Schindler C, Jéquier E, Tappy L

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Calcium Acetate Side Effects

Calcium acetate E263 is a calcium salt of acetic acid. It is used n food as used as a chelating agent, suppressing mold agent, stabilizer, buffer, flavoring agent, preservative, curing agent, and nutrition fortifie. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Calcium Acetate E263?

Calcium Acetate E263 comes as a hemihydrate in the form of a fine white bulky powder or granular grade that is used as a sequestrant, thickener, or for pH control. Calcium Acetate is mainly used in the production of candy products, desserts, and baked good (bread, cakes, pastries).

Possible Side Effects of Calcium Acetate E263

Though Calcium Acetate E263 is regarded as safe supplement, there maybe some side effects (from drugs.com):

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking calcium acetate:

More common:

  • Abdominal or stomach pain
  • confusion
  • constipation
  • depression
  • dry mouth
  • full or partial loss of consciousness
  • headache
  • incoherent speech
  • increased urination
  • loss of appetite
  • metallic taste
  • muscle weakness
  • nausea or vomiting
  • thirst
  • unusual tiredness
  • weight loss

Incidence not known:

  • Swelling

Minor Side Effects

Some of the side effects that can occur with calcium acetate may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

  • Diarrhea

Less common:

  • Itching

Incidence not known:

  • Dizziness
  • weakness

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Calcium Acetate is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Calcium Acetate populations. Better consult to your doctor if you would like to intake Calcium Acetate E263.

 

 

Related Research

1. Efficacy and safety of sevelamer hydrochloride and calcium acetate in patients on peritoneal dialysis [Nephrol Dial Transplant. 2009 Jan] Author: Evenepoel P, Selgas R, Caputo F, Foggensteiner L, Heaf JG, Ortiz A, Kelly A, Chasan-Taber S, Duggal A, Fan S.

2. Comparative effectiveness of calcium acetate and sevelamer on clinical outcomes in elderly hemodialysis patients enrolled in medicare part d. [Am J Kidney Dis. 2014 Jul] Author: Yusuf AA, Weinhandl ED, St Peter WL.

3. A comparison of calcium acetate/magnesium carbonate and sevelamer-hydrochloride effects on fibroblast growth factor-23 and bone markers: post hoc evaluation from a controlled, randomized study. [Nephrol Dial Transplant. 2013 Sep] Author: Covic A, Passlick-Deetjen J, Kroczak M, Büschges-Seraphin B, Ghenu A, Ponce P, Marzell B, de Francisco AL.

4. Comparison of calcium acetate and sevelamer on vascular function and fibroblast growth factor 23 in CKD patients: a randomized clinical trial. [Am J Kidney Dis. 2012 Feb] Author: Yilmaz MI, Sonmez A, Saglam M, Yaman H, Kilic S, Eyileten T, Caglar K, Oguz Y, Vural A, Yenicesu M, Mallamaci F, Zoccali C.

5. Effect of lanthanum carbonate and calcium acetate in the treatment of hyperphosphatemia in patients of chronic kidney disease. [Indian J Pharmacol. 2009 Aug] Author: Scaria PT, Gangadhar R, Pisharody R.

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Potassium Acetate Anhydrous Side Effects

Potassium Acetate E261 is a white crystalline powder with a salty taste. It is used as a preservative, acidity regulator, buffer, corrective, and color protector. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Potassium Acetate E261?

Potassium acetate E261 (KCH3COO) is the potassium salt of acetic acid. Potassium acetate is used as a food additive as a preservative and acidity regulator.

Possible Side Effects of Potassium Acetate E261

Though Potassium Acetate E261is regarded as safe supplement, there maybe some side effects:

  • symptoms of potassium intoxication which are tingling or burning sensation in hands and feet
  • weakness
  • lack of muscle tone
  • listlessness
  • mental confusion
  • weakness and heaviness of the legs
  • low blood pressure
  • diarrhea, or
  • heart irregularities

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Potassium Acetate E261 is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Potassium Acetate populations. Better consult to your doctor if you would like to intake Potassium Acetate E261.

Related Research

1. Potassium acetate and potassium lactate enhance the microbiological and physical properties of marinated catfish fillets. [J Food Sci. 2011 May] Author: Kin S, Schilling MW, Smith BS, Silva JL, Kim T, Pham AJ, Campano SG.

2. Water-mediated potassium acetate intercalation in kaolinite as revealed by molecular simulation. [J Mol Model. 2014 Mar] Author: Ható Z, Makó É, Kristóf T.

3. Mechanism of dehydroxylation temperature decrease and high temperature phase transition of coal-bearing strata kaolinite intercalated by potassium acetate. [J Colloid Interface Sci. 2012 Jun 15] Author: Cheng H, Liu Q, Cui X, Zhang Q, Zhang Z, Frost RL.

4. Delamination of kaolinite-potassium acetate intercalates by ball-milling. [J Colloid Interface Sci. 2010 Aug 15] Author: Cheng H, Liu Q, Zhang J, Yang J, Frost RL.

5. Simulation-assisted evidence for the existence of two stable kaolinite/potassium acetate intercalate complexes. [J Colloid Interface Sci. 2010 Sep 1] Author: Makó E, Rutkai G, Kristóf T.

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Calcium Propionate Side Effects

Calcium Propionate E282 is a calcium salt mainly used as a preservative in bakery applications. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Calcium Propionate E282?

Calcium Propionate E282 appears as a white powder. It is mainly used as a food preservative in a wide variety of products, including but not limited to bread, other baked goods, processed meat, whey, and other dairy products. It occurs naturally in butter and some types of cheese. It is also used in bakery products as a mold inhibitor, it keeps bread and baked goods from spoiling by preventing mold and bacterial growth.

Possible Side Effects of Calcium Propionate E282

Though Calcium Propionate E282 is regarded as safe supplement, there maybe some side effects: damage your stomach lining by exacerbating gastritis and inducing severe ulcers and cause irritability, restlessness, inattention and sleep disturbance.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Calcium Propionate E282 is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Calcium Propionate E282 populations. Better consult to your doctor if you would like to intake Calcium Propionate E282.

Related Research

1. Alpacas fed calcium propionate seem to moderate their energy intake. [J Anim Physiol Anim Nutr (Berl). 2014 Mar 13] Author: Lund KE, Milton JT, Maloney SK, Blache D.

2. The effect of sourdough and calcium propionate on the microbial shelf-life of salt reduced bread. [Appl Microbiol Biotechnol. 2012 Oct] Author: Belz MC, Mairinger R, Zannini E, Ryan LA, Cashman KD, Arendt EK.

3. The use of sourdough fermented by antifungal LAB to reduce the amount of calcium propionate in bread. [Int J Food Microbiol. 2008 Jul 31] Author: Ryan LA, Dal Bello F, Arendt EK.

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Cocoa Powder Side Effects

Cocoa Powder can be used in baking applications to make chocolate, desserts, drinks, confectionery and ice-cream products. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Cocoa Powder?

Cocoa Powder is a free flowing brown powder which is obtained from cocoa solids, one of the two components of chocolate liquor. Chocolate liquor is a substance which is obtained during the manufacturing process which turns cocoa beans into chocolate products. This product has a fat content of 10%-12%. Cocoa Powder can be added to baked goods for a chocolate flavor, whisked with hot milk or water for hot chocolate, and used in a variety of other ways.

Possible Side Effects of Cocoa Powder

Though Cocoa Powder is regarded as safe supplement, there maybe some side effects:

Anxiety: There is the concern that caffeine in the large amounts of cocoa may make the anxiety disorders worse.

Diabetes: Cocoa appears to raise the blood sugar levels as well as may interfere with the blood sugar control in the people having diabetes.

Diarrhea: Cocoa has caffeine and caffeine in cocoa, particularly when taken in the large amounts, will worsen diarrhea.

Gastroesophageal Reflux Disease: Cocoa appears to hinder effectiveness of valve in food tube, which keeps contents of stomach to come back in food tube or airway. This can make symptoms of the GERD worse.

Migraine headaches: Cocoa may trigger the migraines in many sensitive people.

Irritable bowel syndrome: Cocoa has caffeine. Caffeine in cocoa, particularly when taken in the large amounts, will worsen diarrhea & may worsen the symptoms of IBS.

Surgery: Cocoa may interfere with the blood sugar control during surgical procedures.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Cocoa Powder is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Cocoa Powder populations. Better consult to your doctor if you would like to intake Cocoa Powder.

Related Research

1. Microbiota of cocoa powder with particular reference to aerobic thermoresistant spore-formers. [Food Microbiol. 2011 May] Author: Lima LJ, Kamphuis HJ, Nout MJ, Zwietering MH.

2. A new process to develop a cocoa powder with higher flavonoid monomer content and enhanced bioavailability in healthy humans. [J Agric Food Chem. 2007 May 16] Author: Tomas-Barberan FA, Cienfuegos-Jovellanos E, Marín A, Muguerza B, Gil-Izquierdo A, Cerda B, Zafrilla P, Morillas J, Mulero J, Ibarra A, Pasamar MA, Ramón D, Espín JC.

3. Flavan-3-ol fraction from cocoa powder promotes mitochondrial biogenesis in skeletal muscle in mice. [Lipids Health Dis. 2014 Apr 5] Author: Watanabe N, Inagawa K, Shibata M, Osakabe N.

4. Tolerance for high flavanol cocoa powder in semisweet chocolate. [Nutrients. 2013 Jun 21] Author: Harwood ML, Ziegler GR, Hayes JE.

5. Cocoa powder extracts exhibits hypolipidemic potential in cholesterol-fed rats. [Afr J Med Med Sci. 2012 Dec] Author: Nwichi SO, Adewole EK, Dada AO, Ogidiama O, Mokobia OE, Farombi EO.

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Sodium Aluminium Phosphate Side Effects

Sodium Aluminum Phosphate (SALP) E541 is a leavening agent. It is often used in baking powders. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Sodium Aluminum Phosphate E541?

Sodium Aluminum Phosphate E541 is a slow/heat reactive leavening acid. It can be used in a wide range of bakery applications by itself or in combination with other leavening acids. It is used specifically as a leavening agent in baking powders and in institutional and retail cake, cookie, muffin, and pancake mixes.

Possible Side Effects of Sodium Aluminum Phosphate E541

Though Sodium Aluminum Phosphate E541 is regarded as safe supplement, there maybe some side effects:

Possible long-term side effects

  • anemia
  • bone problems
  • constipation
  • chronic aluminum toxicity (with extremely high doses)
  • brain damage (with extremely high doses)

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium Aluminum Phosphate is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sodium Aluminum Phosphate populations. Better consult to your doctor if you would like to intake Sodium Aluminum Phosphate E541.

 

 

Related Research

1. Toxicity and aluminium concentration in bone following dietary administration of two sodium aluminium phosphate formulations in rats. [Food Chem Toxicol. 1987 Jul] Author: Hicks JS, Hackett DS, Sprague GL.

2. Toxicity and aluminium concentration in bone following dietary administration of two sodium aluminium phosphate formulations in rats. [Food Chem Toxicol. 1987 Jul] Author: Hicks JS, Hackett DS, Sprague GL.

3. A 6-month dietary toxicity study of acidic sodium aluminium phosphate in beagle dogs. [Food Chem Toxicol. 1984 Jan] Author: Katz AC, Frank DW, Sauerhoff MW, Zwicker GM, Freudenthal RI

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Sodium Hexametaphosphate Side Effects

Sodium hexametaphosphate is primarily used as an emulsifier, texturizer in many foods and as an anti-staining agent in toothpaste. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Sodium Hexametaphosphate?

Sodium Hexametaphosphate (Food Grade) is in the form of white powder, white fine powder, white granular or colorless piece. In the food industry it is used as a sequesdtrant and quality improver. Applications for Sodium Hexametaphosphate include cheese powders and dips, breakfast cereals, beer and bottled beverages, imitation cheese, frozen dessert, packaged eggs and artificial maple syrup.

Possible Side Effects of Sodium Hexametaphosphate

Though Sodium Hexametaphosphate is regarded as safe supplement, there maybe some side effects:

Possible short-term side effects

  • headache
  • nausea
  • vomiting
  • dizziness
  • gastrointestinal irritation
  • allergic reaction

Possible long-term side effects

  • pancreatic cancer
  • loss of calcium
  • kidney problems
  • skin irritation

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium Hexametaphosphate is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sodium Hexametaphosphate populations. Better consult to your doctor if you would like to intake Sodium Hexametaphosphate.

 

 

Related Research

1. Anticalculus efficacy and safety of a stabilized stannous fluoride/sodium hexametaphosphate dentifrice. [Compend Contin Educ Dent. 2005 Sep] Author: Schiff T, Saletta L, Baker RA, He T, Winston JL.

2. Phosphate: are we squandering a scarce commodity? [Nephrol Dial Transplant. 2014 Sep] Author: Ferro CJ1, Ritz E2, Townend JN3.

3. Final report on the safety assessment of Sodium Metaphosphate, Sodium Trimetaphosphate, and Sodium Hexametaphosphate. [Int J Toxicol. 2001] Author: Lanigan RS.

4. Anticalculus efficacy and safety of a novel whitening dentifrice containing sodium hexametaphosphate: a controlled six-month clinical trial. [J Clin Dent. 2002] Author: Liu H, Segreto V, Baker R, Vastola K, Ramsey L, Gerlach R.

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