Calcium Gluconate E578 is a mineral supplement that is manufactured by the neutralization of gluconic acid with lime or calcium carbonate. It is in the form of a white crystal powder and has the chemical formula of C12H22CaO14H2O. Calcium Gluconate can be used in nutritional supplements and nutrition bars. Though it’s considered safe, some are convinced it has potentially dangerous health effects.
What Is Calcium Gluconate E578?
Calcium Gluconate E578 is a white crystalline granule or powder that functions as a firming agent, formulation aid, sequestrant, and stabilizer. It is used as a source of calcium ions for sodium alginate gels, and as a calcium fortifier in baked goods, puddings, and dairy product analogs. It can also mask the bitter aftertaste of some artificial sweeteners.
Possible Side Effects of Calcium Gluconate E578
Although Calcium Gluconate E578 generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:
- nausea
- vomiting
- decreased appetite
- constipation
- dry mouth
- increased thirst
- increased urination
- tingling sensations
GRAS Affirmation: Yes
Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Calcium Gluconate E578 is considered safe.
Suggested Dosage
NA.
Special Populations Precaution
There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Calcium Gluconate populations. Better consult to your doctor if you would like to intake Calcium Gluconate.
Related Research
1. Physical Compatibility of Sodium Glycerophosphate and Calcium Gluconate in Pediatric Parenteral Nutrition Solutions. [JPEN J Parenter Enteral Nutr. 2014 Apr 2] Author: Mackay M, Anderson C.
2. Calcium gluconate infusion is as effective as the vascular endothelial growth factor antagonist cabergoline for the prevention of ovarian hyperstimulation syndrome. [J Hum Reprod Sci. 2013 Oct] Author: Naredi N, Karunakaran S.
3. Protective effects of calcium gluconate on osteoarthritis induced by anterior cruciate ligament transection and partial medial meniscectomy in Sprague-Dawley rats. [J Orthop Surg Res. 2014 Mar 7] Author: Kang SJ, Kim JW, Kim KY, Ku SK, Lee YJ.
4. Clinical arterial infusion of calcium gluconate: the preferred method for treating hydrofluoric acid burns of distal human limbs. [Int J Occup Med Environ Health. 2014 Jan] Author: Zhang Y, Ni L, Wang X, Jiang R, Liu L, Ye C, Xia W, Han C.
5. The clinical effectiveness of the intravenous infusion of calcium gluconate for treatment of hydrofluoric acid burn of distal limbs. [Burns. 2014 Jun] Author: Zhang Y, Wang X, Ye C, Liu L, Jiang R, Ni L, Xia W, Han C.